ARDB-Antibiotic Resistance Genes Database

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OrganismStreptococcus pyogenes MGAS315
Database LinkNCBI Taxon ID: 198466
NCBI Genome Project ID: 311

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_004070AE0140741900521


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
NP_664191chromosomeZP_0220707055.88%vanug%vancomycin vang vanrg vansg vantg vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_664368chromosomeYP_00117612853.37%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_664154chromosomeEDK7936052.02%pmra%ciprofloxacin norfloxacin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
NP_665539chromosomeQ8XED051.83%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_664696chromosomeYP_00158879341.95%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_664964chromosomeQ83LR741.18%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_665537chromosomeABB5334940.93%vanrb%vancomycin vanb vanhb vansb vanwb vanxb vanyb VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Below Similarity Cutoff Genes
NP_665205chromosomeAAC9545654.60%pbp2x80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)