ARDB-Antibiotic Resistance Genes Database

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OrganismBacillus anthracis str. Ames
Database LinkNCBI Taxon ID: 198094
NCBI Genome Project ID: 309

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_003997AE0168795227293


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
NP_845780chromosomeAAK53751100.00%bl2a_1%penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
NP_845373chromosomeZP_00393267100.00%%
NP_844879chromosomeNP_83223390.61%bl2a_iii%penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
NP_842835chromosomeYP_00137362187.76%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
NP_846348chromosomeABS7348069.57%fosb%fosfomycin Glutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin
NP_843352chromosomeBAA1235565.39%blt%chloramphenicol doxorubicin fluoroquinolone puromycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
NP_844444chromosomeABS7348064.23%fosb%fosfomycin Glutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin
NP_843860chromosomeABF0515962.17%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
NP_844991chromosomeAAC6167160.29%vatc%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
NP_844786chromosomeP2682556.94%cata16%chloramphenicol Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
NP_847562chromosomeAAA8687156.60%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
NP_846663chromosomeCAA0558855.77%ykkc%na_antimicrobials ykkd Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
NP_847290chromosomeAAY5200754.48%vanya%teicoplanin vancomycin vana vanha vanra vansa vanxa VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_846664chromosomeABS7365453.85%ykkd%na_antimicrobials ykkc Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
NP_842833chromosomeABF0515952.59%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
NP_842823chromosomeABA7172750.85%vanrg%vancomycin vang vansg vantg vanug vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_847656chromosomeYP_00117612849.32%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_844929chromosomeABA7172748.94%vanrg%vancomycin vang vansg vantg vanug vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_846150chromosomeYP_00109629448.56%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
NP_843317chromosomeYP_00117612848.42%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_844293chromosomeAAL2744548.23%vanre%vancomycin vane vanse vante vanxye VanE type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_846980chromosomeYP_00137362147.83%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
NP_843449chromosomeBAA2222847.73%lmrb%lincomycin ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
NP_845382chromosomeQ83LR746.61%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_843538chromosomeBAA2222846.19%lmrb%lincomycin ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
NP_847292chromosomeAAZ9883546.02%vanrd%teicoplanin vancomycin vand vanhd vansd vanxd vanyd VanD type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_844038chromosomeBAA7457245.92%mphb%macrolide Macrolide phosphotransferase
NP_846982chromosomeABK8618845.65%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_842837chromosomeABK8618844.69%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_847798chromosomeP4233244.37%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
NP_845870chromosomeNP_84816744.37%catb2%chloramphenicol Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
NP_845298chromosomeCAD6019643.68%aac6ie%amikacin dibekacin isepamicin netilmicin sisomicin tobramycin Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
NP_844275chromosomeYP_00157087143.49%mdtg%deoxycholate fosfomycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
NP_844857chromosomeQ3Z3Q443.44%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_843605chromosomeAAL2744542.92%vanre%vancomycin vane vanse vante vanxye VanE type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_847861chromosomeAAY5200242.54%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_843778chromosomeAAL2744542.04%vanre%vancomycin vane vanse vante vanxye VanE type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_844368chromosomeABP5733042.03%ant6ia%streptomycin Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
NP_843349chromosomeABS7365341.82%ykkc%na_antimicrobials ykkd Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
NP_847664chromosomeAAL2744541.23%vanre%vancomycin vane vanse vante vanxye VanE type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_844249chromosomeZP_0083476341.09%%
NP_847036chromosomeABA7172740.59%vanrg%vancomycin vang vansg vantg vanug vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_843182chromosomeCAB6122940.53%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_843949chromosomeABA7172740.52%vanrg%vancomycin vang vansg vantg vanug vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_844604chromosomeABK8618840.52%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_844470chromosomeAAY5200740.28%vanya%teicoplanin vancomycin vana vanha vanra vansa vanxa VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_847275chromosomeQ83LR740.18%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_843834chromosomeP4233240.15%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
NP_847582chromosomeAAG0898340.11%vgaa%streptogramin_a ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
Below Similarity Cutoff Genes
NP_843078chromosomeEDJ9155548.09%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
NP_844899chromosomeAAO4311041.05%lsa80%lincosamide macrolide streptogramin_b ABC efflux family that is resistant to MLS antibiotics