ARDB-Antibiotic Resistance Genes Database

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OrganismStaphylococcus epidermidis ATCC 12228
Database LinkNCBI Taxon ID: 176280
NCBI Genome Project ID: 279

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_004461AE0159292499279
plasmid pSE-12228-06NC_005003AE0159356585
plasmid pSE-12228-05NC_005004AE01593424365
plasmid pSE-12228-04NC_005005AE01593317261
plasmid pSE-12228-03NC_005006AE0159328007
plasmid pSE-12228-02NC_005007AE0159314679
plasmid pSE-12228-01NC_005008AE0159304439


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
NP_765163chromosomeNP_76516382.56%bl2a_pc%penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
NP_863256plasmid pSE-12228-01CAI5978780.39%tetk%tetracycline Major facilitator superfamily transporter, tetracycline efflux pump.
NP_763786chromosomeABS7348057.55%fosb%fosfomycin Glutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin
NP_765432chromosomeCAA0558845.78%ykkc%na_antimicrobials ykkd Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
NP_764924chromosomeAAY6797144.87%vanrc%vancomycin vanc vansc vant vanxyc VanC type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_764100chromosomeAAG2169544.23%vate%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
NP_764009chromosomeYP_00117817043.56%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
NP_763573chromosomeBAE9611342.92%vanrd%teicoplanin vancomycin vand vanhd vansd vanxd vanyd VanD type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_765961chromosomeYP_00157104142.47%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_764674chromosomeCAE5342440.52%dfra20%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.