ARDB-Antibiotic Resistance Genes Database

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OrganismStreptococcus pyogenes M1 GAS
Database LinkNCBI Taxon ID: 160490
NCBI Genome Project ID: 269

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_002737AE0040921852441


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
NP_268817chromosomeZP_0220707057.35%vanug%vancomycin vang vanrg vansg vantg vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_269046chromosomeYP_00117612853.37%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_268780chromosomeEDK7936052.27%pmra%ciprofloxacin norfloxacin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
NP_269980chromosomeQ8XED051.83%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_269231chromosomeYP_00138962147.14%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
NP_269247chromosomeYP_00137362145.54%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
NP_269390chromosomeYP_00158879341.53%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_269978chromosomeABB5334940.93%vanrb%vancomycin vanb vanhb vansb vanwb vanxb vanyb VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_269582chromosomeQ83LR740.27%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Below Similarity Cutoff Genes
NP_269705chromosomeAAC9545652.79%pbp2x80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)