ARDB-Antibiotic Resistance Genes Database

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OrganismStaphylococcus aureus subsp. aureus N315
Database LinkNCBI Taxon ID: 158879
NCBI Genome Project ID: 264

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_002745BA0000182814816
plasmid pN315NC_003140AP00313924653


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
NP_373289chromosomeBAE06288100.00%aad9ib%spectomycin streptomycin Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
NP_375257chromosomeBAE06288100.00%aad9ib%spectomycin streptomycin Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
NP_374024chromosomeBAE06288100.00%aad9ib%spectomycin streptomycin Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
NP_374768chromosomeBAE06288100.00%aad9ib%spectomycin streptomycin Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
NP_373279chromosomeCAH17572100.00%mecr1%methicillin Methicillin-resistance regulatory protein for mecA
NP_373272chromosomeBAB56196100.00%ble%bleomycin Binding protein with a strong affinity to the bleomycin family of antibiotics, which confers resistance to these antibiotics by preventing the bleomycin-induced DNA breakage
NP_375711chromosomeBAE06288100.00%aad9ib%spectomycin streptomycin Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
NP_373569chromosomeQ99WP2100.00%mepa%tigecycline Multi antimicrobial extrusion (MATE) efflux family protein. Multidrug resistance efflux pump.
NP_373278chromosomeABQ9663998.45%meca%beta_lactam Penicillin binding protein, which has a low affinity for beta-lactams and catalyze a penicillin-insensitive transpeptidation.
NP_373273chromosomeBAB5619795.31%aadd%kanamycin tobramycin Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
NP_374767chromosomeBAE0628994.65%erma%lincosamide macrolide streptogramin_b rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
NP_374025chromosomeBAE0628994.65%erma%lincosamide macrolide streptogramin_b rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
NP_373288chromosomeBAE0628994.65%erma%lincosamide macrolide streptogramin_b rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
NP_375256chromosomeBAE0628994.65%erma%lincosamide macrolide streptogramin_b rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
NP_375710chromosomeBAE0628994.65%erma%lincosamide macrolide streptogramin_b rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
NP_395546plasmid pN315BAE9284491.81%bl2a_pc%penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
NP_375446chromosomeABS7348061.31%fosb%fosfomycin Glutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin
NP_374529chromosomeABK8618849.50%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_373972chromosomeYP_00103809448.08%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
NP_373893chromosomeYP_00117817046.10%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
NP_373435chromosomeAAX6480345.70%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_373256chromosomeCAB6122944.83%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_374804chromosomeCAL9094342.24%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_373905chromosomeBAA1260141.02%bmr%chloramphenicol fluoroquinolone Major facilitator superfamily transporter. Multidrug resistance efflux pump.
NP_375742chromosomeQ83LR740.37%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_375523chromosomeYP_00117612840.36%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Below Similarity Cutoff Genes
NP_373374chromosomeAAV8046477.56%tet3880%tetracycline Major facilitator superfamily transporter, tetracycline efflux pump.