ARDB-Antibiotic Resistance Genes Database

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OrganismStaphylococcus aureus subsp. aureus Mu50
Database LinkNCBI Taxon ID: 158878
NCBI Genome Project ID: 263

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_002758BA0000172878529
plasmid VRSApNC_002774AP00336725107


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
NP_370566chromosomeCAH17572100.00%mecr1%methicillin Methicillin-resistance regulatory protein for mecA
NP_370858chromosomeQ99WP2100.00%mepa%tigecycline Multi antimicrobial extrusion (MATE) efflux family protein. Multidrug resistance efflux pump.
NP_370577chromosomeBAE06288100.00%aad9ib%spectomycin streptomycin Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
NP_370558chromosomeBAB56196100.00%ble%bleomycin Binding protein with a strong affinity to the bleomycin family of antibiotics, which confers resistance to these antibiotics by preventing the bleomycin-induced DNA breakage
NP_372180chromosomeBAE06288100.00%aad9ib%spectomycin streptomycin Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
NP_370565chromosomeABQ9663998.45%meca%beta_lactam Penicillin binding protein, which has a low affinity for beta-lactams and catalyze a penicillin-insensitive transpeptidation.
NP_370922chromosomeQ932I898.44%tetm%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
NP_115315plasmid VRSApCAL2289597.49%aac6ie%amikacin dibekacin isepamicin netilmicin sisomicin tobramycin Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
NP_370559chromosomeBAB5619795.31%aadd%kanamycin tobramycin Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
NP_370576chromosomeBAE0628994.65%erma%lincosamide macrolide streptogramin_b rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
NP_372179chromosomeBAE0628994.65%erma%lincosamide macrolide streptogramin_b rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
NP_115321plasmid VRSApBAE9285386.58%qaca%qa_compound qacb Multidrug efflux pump from bacterial pathogen staphylococcus aureus. Including QacA and QacB, both of which confer resistance to various toxic organic cations but differ in that QacB mediates lower levels of resistance to divalent cations. They differed by seven nucleotide subsititutions.
NP_372857chromosomeABS7348061.31%fosb%fosfomycin Glutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin
NP_371286chromosomeYP_00103809448.08%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
NP_371207chromosomeYP_00117817046.10%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
NP_370722chromosomeAAX6480345.70%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_370542chromosomeCAB6122944.83%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_372217chromosomeCAL9094342.24%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_371219chromosomeBAA1260141.02%bmr%chloramphenicol fluoroquinolone Major facilitator superfamily transporter. Multidrug resistance efflux pump.
NP_373147chromosomeQ83LR740.37%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_372936chromosomeYP_00117612840.36%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Below Similarity Cutoff Genes
NP_370661chromosomeAAV8046477.56%tet3880%tetracycline Major facilitator superfamily transporter, tetracycline efflux pump.