ARDB-Antibiotic Resistance Genes Database

HOME DOCUMENTATION BLAST ADVANCED  SEARCH BROWSE
     Help

OrganismNeisseria meningitidis Z2491
Database LinkNCBI Taxon ID: 122587
NCBI Genome Project ID: 252

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_003116AL1579592184406


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
NP_284770chromosomeCAM09174100.00%pbp2b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
NP_284788chromosomeNP_78329951.81%qac%qa_compound Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
NP_283690chromosomeABG6809549.62%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
NP_283527chromosomeYP_00143854146.91%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_284113chromosomeCAA3747743.80%otra%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
NP_284775chromosomeYP_00117817043.61%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
NP_284674chromosomeNP_59811443.18%mexd%erythromycin fluoroquinolone glycylcycline roxithromycin mexc oprj Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_284675chromosomeCAC3572441.86%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_283449chromosome1XAT41.54%catb4%chloramphenicol Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
NP_283594chromosomeABK8618840.76%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_284872chromosomeCAL4845740.62%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Below Similarity Cutoff Genes
NP_283462chromosomeEDJ9155540.97%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)