ARDB-Antibiotic Resistance Genes Database

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OrganismStreptomyces coelicolor A3(2)
Database LinkNCBI Taxon ID: 100226
NCBI Genome Project ID: 242

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_003888AL6458828667507
plasmid SCP1NC_003903AL589148356023
plasmid SCP2NC_003904AL64577131317


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
NP_630216chromosomeCAC3395393.85%fush%fusidic_acid Esterase enzyme inactivating fusidic acid
NP_630197chromosomeCAC3393491.15%ermo%lincosamide macrolide streptogramin_b rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
NP_625085chromosomeCAC1434886.27%tet80%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
NP_733568chromosomeCAD5530376.87%tcma%tetracenomycin_c Major facilitator superfamily transporter. Resistance to tetracenomycin C by an active tetracenomycin C efflux system which is probably energized by transmembrane electrochemical gradients.
NP_627790chromosomeAAM0984964.52%vand%teicoplanin vancomycin vanhd vanrd vansd vanxd vanyd VanD type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_627791chromosomeNP_81595063.86%vanxb%vancomycin vanb vanhb vanrb vansb vanwb vanyb VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_627789chromosomeAAY5200462.66%vanha%teicoplanin vancomycin vana vanra vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_733498chromosomeP2525661.36%tlrc%lincosamide macrolide streptogramin_b ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
NP_626184chromosomeAAN8081159.65%emre%aminoglycoside emrd Multidrug resistance efflux pump.
NP_733633chromosomeCAA0738156.23%aph6ib%streptomycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
NP_628278chromosomeAAF2417154.55%vate%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
NP_626956chromosomeYP_00109629447.39%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
NP_625118chromosomeYP_00133457845.87%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_628826chromosomeQ8ZQE444.95%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_627945chromosomeYP_00133457844.91%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_624622chromosomeAAG2169544.28%vate%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
NP_630302chromosomeCAC3395344.27%fush%fusidic_acid Esterase enzyme inactivating fusidic acid
NP_628336chromosomeABB5336844.09%vanrb%vancomycin vanb vanhb vansb vanwb vanxb vanyb VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_627438chromosomeP4233243.13%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
NP_629532chromosomeP4233242.92%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
NP_626522chromosomeYP_00145376042.86%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_626909chromosomeYP_00145376042.79%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_629089chromosomeYP_00143854142.47%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_628525chromosomeBAE0628842.25%aad9ib%spectomycin streptomycin Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
NP_630452chromosomeP4233242.18%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
NP_626464chromosomeABB5336842.17%vanrb%vancomycin vanb vanhb vansb vanwb vanxb vanyb VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_630792chromosomeYP_00143854141.77%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_631748chromosomeYP_25422141.18%mphc%macrolide Macrolide phosphotransferase
NP_627308chromosomeYP_00158879341.12%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_629357chromosomeAAN8081141.07%emre%aminoglycoside emrd Multidrug resistance efflux pump.
NP_630752chromosomeYP_00157104141.07%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_630458chromosomeYP_00143854140.93%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_629534chromosomeYP_00137362140.77%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
NP_629187chromosomeYP_00145376040.64%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_625480chromosomeCAD5530340.62%tcma%tetracenomycin_c Major facilitator superfamily transporter. Resistance to tetracenomycin C by an active tetracenomycin C efflux system which is probably energized by transmembrane electrochemical gradients.
NP_733586chromosomeAAC1577540.40%otrb%tetracycline Major facilitator superfamily transporter, tetracycline efflux pump.
NP_627329chromosomeYP_00157104140.18%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_627943chromosomeYP_00157104140.09%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Below Similarity Cutoff Genes
NP_631702chromosomeCAC1699566.07%cml_e595%chloramphenicol Major facilitator superfamily transporter, chloramphenicol efflux pump.
NP_631570chromosomeAAB3656858.90%cml_e695%chloramphenicol Major facilitator superfamily transporter, chloramphenicol efflux pump.