ARDB-Antibiotic Resistance Genes Database

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AccessionAAV74561
Sequence StatusNON-REDUNDANT
COMPLETE
Resistance Typevanb
Requirevanxb    vanwb    vanrb    vanyb    vansb    vanhb    
DescriptionVanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Antibiotic Resistancevancomycin
OrganismClostridium sp. MLG856-1
Gene Ontology (GO)Molecular Function
D-alanine-D-alanine ligase activity [GO:0008716]


Biological Process
drug target replacement [AR:0001002]
vancomycin resistance [AR:0000028]
COGCOG1181
Description: D-alanine-D-alanine ligase and related ATP-grasp enzymes
Function: Cell wall/membrane/envelope biogenesis;

CDD110791
134632
141725
Database LinkNCBI Protein: AAV74561
NCBI DNA: AY655710      
Protein Sequence