ARDB-Antibiotic Resistance Genes Database

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Your Query:     Database: Resistance Gene(ALL)    Genus: Shigella    

494 resistance genes are found

Gene IDGene TypeResistance ProfileDescription
ABF06117mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_410370mdtnacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAZ87225acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_405948mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_401803ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

NP_709855mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_312992mdtoacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_403670mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAZ87811mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABB67996mdtedoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_409972mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q3Z351mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q3YWK3mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAZ90435ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

AAG14405sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03064101tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABC97687ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_783828tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ABB64281bl1_eccephalosporin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_001881078arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

EDX35468tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

NP_838053sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

Q83IQ8mdtoacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAP15940acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABB61073bcr

ACD08584acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABC97682ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

NP_706007ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_001882199mdtedoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03064786tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ABB62374mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

NP_706764macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAZ90756mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

Q83PL6mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAD88773bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACD08901mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABC97697ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABB67411tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAP16343macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

B2U2G8mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABC97678ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_001139956aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

AAZ87793mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_783830sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

YP_408416mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAZ90824bl1_eccephalosporin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_691296mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

NP_838841mdtnacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAP18650mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABB64066emrdMultidrug resistance efflux pump.

ABB66588mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABL09147bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

NP_836538macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAZ90109mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAS79110ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_409825mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABB64107mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABB62179mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACD08893bl1_eccephalosporin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABU97160dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

NP_707822emreaminoglycoside; Multidrug resistance efflux pump.

YP_403865mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABB69931bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_688009acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDX36637mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

NP_839698bl1_eccephalosporin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABB68803mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_689427emreaminoglycoside; Multidrug resistance efflux pump.

AAT72892dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ACI42280qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

AAP16301mdfa

ABC97665ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

BAE73190ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

AAA72107aac6iaamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

ZP_03065057acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03064581mdtnacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_402564bcr

ACD10103macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_691420mdtnacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDX35382mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABC97681ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABF02332ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

BAE53778bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAP18366tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDX35509mdtoacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_406604ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABO87505sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

YP_410369mdtoacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABC97674ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAM21665aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

Q32DT3arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

NP_709522emrdMultidrug resistance efflux pump.

ABB65485macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_001882844bl1_eccephalosporin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_690464bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ACM67495qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

YP_402153acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_310028mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAN41648dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

EDX36244tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAP18386bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

NP_708867bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_310895emreaminoglycoside; Multidrug resistance efflux pump.

YP_001139955aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

AAL75562tetdtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

Q83QT8arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ABB62522arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ABB61998mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDX36702emrdMultidrug resistance efflux pump.

AAD50247tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

AAP19510bl1_eccephalosporin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABC97668ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABF02704acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABC97696ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAG14408bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

NP_836134acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAZ89757tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABC97676ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAZ89777bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ABB63513mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDX34735mdfa

AAN45229emrdMultidrug resistance efflux pump.

ABD04053aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

AAD39937dfra7trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

AAZ88961arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ZP_03066975mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

NP_837548emreaminoglycoside; Multidrug resistance efflux pump.

ZP_03063464emrdMultidrug resistance efflux pump.

AAP15939acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

NP_836495mdfa

ABF06289bl1_eccephalosporin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

Q323M3macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_407914mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q0T5W7mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_404013arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

YP_406903acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABF04437arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ABB68144mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAA72106ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

AAL75557tetdtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ABB67997mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAZ87608macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABC97698ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

NP_709856mdtoacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_312991mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_309089ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABB68172emrdMultidrug resistance efflux pump.

YP_688010acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAN41714ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAL36589aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

NP_710019bl1_eccephalosporin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

BAD88772qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ABC86896bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_409258bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ABF06116mdtoacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_406902acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABB65074acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_403489mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAD88776qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

AAP17159mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

NP_837857arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

YP_001880424mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

P0AG06ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_407312macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABC97692ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAN28000dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

YP_691422mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACP40997dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03063547mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAP16344macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABF03096macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAC20911tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

AAZ90757mdtoacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAF72981bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABL09148bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABC97688ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

Q83MG8ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAZ90177emrdMultidrug resistance efflux pump.

AAN45726bl1_eccephalosporin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAL75559tetdtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

NP_838556tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAN45562mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

Q3YZV1arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ABU97157dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ABN41478ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

CAL08007bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

Q0T4A9mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABN49115bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03065389macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_001882916mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAM18213ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ACD06423acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_409824mdtedoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

NP_838840mdtoacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAP15594ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

NP_836133acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_404705tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_312412emrdMultidrug resistance efflux pump.

EDX35118acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACD08684rosafosmidomycin; Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.

ABB64776ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

Q83LR7macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

NP_835789ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAG14407aph3iagentamincin_b; kanamycin; lividomycin; neomycin; paromomycin; ribostamycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

NP_839191mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDX33176mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAE73191dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ACD09046ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_407239mdfa

YP_402154acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABO87507aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_309842macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAN42471macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABC97675ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_405004mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03065442macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABC97695ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ACI42281qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

EDX35577mdtnacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

Q31UW4mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q83LI8mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAP18968emrdMultidrug resistance efflux pump.

Q3Z5V8ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAN42428mdfa

YP_312670ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_410000emrdMultidrug resistance efflux pump.

ZP_03066488bcr

YP_001880762mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABF03856mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAD00086ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

AAL75563tetdtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ABF04122emreaminoglycoside; Multidrug resistance efflux pump.

ABF04376bcr

YP_001881820bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ABD04054catb3chloramphenicol; Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.

Q32ES6mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAL75558tetdtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

YP_688401macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAL08435ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

Q32DZ9macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAP19002mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q3YXI5bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ABO87504tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ABC97670ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABN41476dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

YP_408684arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

AAP18652mdtnacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

NP_709342mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABC97664ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAC97980bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABB62456macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ACD08104mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q321C2mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

NP_838576bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ABB65075acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

Q31WX8bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ABC97673ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABC97691ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_691152emrdMultidrug resistance efflux pump.

NP_709857mdtnacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABC97684ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABC97662ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ACD10105mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

P64177macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABF02705acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_001139954sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

AAN45195mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_783831aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ABU97159ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ABC86897bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACD07082tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABA60617bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_311196arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ABF03055mdfa

NP_708846tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABB60314ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

NP_709488mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAP17605bcr

YP_310046mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAE73196ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ABD04055bl2d_oxa10cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDX34691macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03064089bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_312012bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_001881802tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_312360mdtedoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAN43848arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ABF05816mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAT72894ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

AAS79109bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_001882200mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABB66856arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ABF05847emrdMultidrug resistance efflux pump.

B2U259ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

BAE73193ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_690448tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABC97667ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAZ90758mdtnacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAL08445tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

AAM22221tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ABB68723bl1_eccephalosporin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

NP_839157emrdMultidrug resistance efflux pump.

YP_405005mdtedoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

NP_837350mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q0T2M8arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

AAL75564tetdtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

EDX33652bcr

AAN44574bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_001879173acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAG14406mphamacrolide; Macrolide phosphotransferase

AAP17863sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

Q0T8E4ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAN06705aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

CAN87713dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ACD09471mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABC97686ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAZ87607macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

EDX36785mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAZ88194mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_405557emrdMultidrug resistance efflux pump.

ABC97672ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAM21663sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

YP_689742arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

YP_688360mdfa

ABB60665acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAL08436bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABK60211bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_309460acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAP17357emreaminoglycoside; Multidrug resistance efflux pump.

ACM67494qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

B2TUR5mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_689161mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAF63422bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABJ98409bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABC97694ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAN06712sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

AAN42062acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03066814ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_001882453mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q32FA7mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001880923macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_403948macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

Q0T0K6bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ACD08566bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

Q3Z218mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABC97683ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

EDX36650dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

YP_309843macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

NP_706356acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

P67387bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

AAZ90125mdtedoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAP18651mdtoacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAA72105ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ABC97685ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABF05991mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAL75560tetdtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_03063412dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

Q31YK2arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ACD08433mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

NP_836774mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAA77393bl3_impcarbapenem; cephalosporin; cephamycin; penicillin; Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

Q83P86mdtnacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

NP_706721mdfa

YP_309461acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

NP_837796bcr

AAL08441cata1chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

YP_410551bl1_eccephalosporin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABC97679ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABC97669ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

NP_706986mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAN45564mdtnacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDX36871mdtedoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABJ98411ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ABB68541mdtoacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_409239tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

Q32K43ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

BAE73194dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

YP_691121mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAZ86854ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAN42472macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

Q0SYP9mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAZ87226acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03064513mdtoacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAN28002ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_313059bl1_eccephalosporin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDX36232bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ABB69930bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_688603mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAE73197dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

YP_689681bcr

YP_312993mdtnacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABB68542mdtnacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDX35044acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03063399mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

B2TTK5mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABC97671ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_001879188rosafosmidomycin; Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.

AAN43788bcr

ABB63514mdtedoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABF05143tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACI42279qnrafluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

Q7UAH8mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001882481emrdMultidrug resistance efflux pump.

1QCAcata3chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

EDX34744macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

NP_708141arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

AAN45049mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAC53726sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ABC97663ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABB64457mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABC97693ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ACK43807dfra17trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ABO87506aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ABF06115mdtnacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDX33320ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABC97690ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ACD09525emrdMultidrug resistance efflux pump.

YP_312344mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q31ZC0mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAA27523ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ABO88210aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

YP_405598mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAN42693mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001139953tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_03064700mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

P0AC12sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

AAZ90124mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAG45956bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_403947macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ACD08587mdtedoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABC97677ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAL75561tetdtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

EDX34492arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

AAN45563mdtoacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACR09680aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

YP_410631mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q328Z8mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABF05159bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ACP40995dfra17trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

AAP16580mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABB60664acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABU97161ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_687637ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

Q83P87mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABC97700ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABF03298mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

NP_706765macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABB66086mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAP17667arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

NP_706355acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAM21664aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_03063633mdtedoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAN42063acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_691421mdtoacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03064983acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABC97666ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAN06707tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

AAM21661tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ABC97689ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABB67430bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_001880924macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

Q3Z3Q4macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABB65411mdfa

ABU63585bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

NP_708081bcr

AAN43529emreaminoglycoside; Multidrug resistance efflux pump.

YP_001878864ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

BAE73199bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_783832aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

AAZ88660emreaminoglycoside; Multidrug resistance efflux pump.

CAA77111bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_001879172acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABC97699ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABB62457macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

B2U1G1bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03065589arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

AAN44553tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03065433mdfa

NP_836537macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

NP_838839mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABC97680ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_312359mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABB63214tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAT76431bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACD07332arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

YP_405772bl1_eccephalosporin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABO88213aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

ACD09974macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_407313macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_310429mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_691594bl1_eccephalosporin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_311992tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABB65484macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

Q326I2ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.