ARDB-Antibiotic Resistance Genes Database

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Your Query:     Database: Resistance Gene(ALL)    Genus: Salmonella    

1860 resistance genes are found

Gene IDGene TypeResistance ProfileDescription
ZP_03402998bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ACN47953emrdMultidrug resistance efflux pump.

P74872pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

AAC43973tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002116741emrdMultidrug resistance efflux pump.

ABA54433bl2c_pse1carbenicillin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAR38884tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_209357cml_e1chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

ZP_02656523acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAO69604macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03362156mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACN47366bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ACF89590ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ACH77992mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002145858macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAD31710catb2chloramphenicol; Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.

ABX70035emrdMultidrug resistance efflux pump.

ZP_03216935acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_02662648acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_02681532tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

YP_002243977mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ12453macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_02654651bcr

ZP_03215884ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_002214429acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAS18384dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

AAX67626emrdMultidrug resistance efflux pump.

ACF88509bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_001551788bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

NP_569406cata1chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

CAA08843bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAW80310bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABO41097cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

AAN16909ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_002045964pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_03373387mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_194879bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002149473mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAF92943tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ACF68244sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_02681785pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_03363122mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001468286qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ACN72583qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

EDZ36503acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDX50721emrdMultidrug resistance efflux pump.

ABQ96633sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03386302mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACI29346bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDZ10742pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

YP_002226662mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACH75404mdfa

BAB91584aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

CAD31705ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_02684829tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_02700386macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

EDY28919acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03365318mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAA08850ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

BAD10976ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

NP_863368tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ABL95940dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

CAJ17559bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAA63263bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03075548tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAR36385acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

BAF93088aph6icstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ABL95945sul3sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ACQ77873bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002143884acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

Q5PC81bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

CAH10847ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_002047420acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_009034sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ACH73644pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_03337773bcr

AAM92462ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

EDZ01106acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_215847mdfa

EDZ35094bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_002113507acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002112974cata2chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

YP_002215984mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001587496pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

EDZ24553tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACF61363bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_02663224bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_002039718acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDX49513macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAL20096mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03346238macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_04653844bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_002040407mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAS76373bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABB71176dfra25trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03405322macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ACH75377bcr

CAR58719bcr

EDZ11168bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

CAD31709ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03358374bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

BAD72947bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

Q57TH0ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABD46713ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

CAG34237bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_02664558sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

YP_002227155bcr

ZP_03386010mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

Q5PGW7mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001573163acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03385675mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAD08278mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABX21900macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03407000acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

NP_569429tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ACF88858macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

B5QV34mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDX45490ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAP43641bl2d_oxa2cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAK61182dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_02684205ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_001911158tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

YP_001571461acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002145456acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

P0A255aac3iiadibekacin; gentamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

ZP_03379907macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

EDZ03809bcr

ZP_03407411tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_02659903ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAK02048sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03385761mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABS88257dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

YP_002038880tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

YP_002244306bcr

ABX68461acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_02669694mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ34369macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAO84013bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03364980pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ABI63552qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ZP_03338460bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

AAN46367dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03385651mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ37575tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

CAR33204mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDX49073mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAS76314dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

CAR32432macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03164300mdfa

CAR59922macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ACF62806pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

YP_002112912tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ABA56511cata1chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

AAO72006mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDY27194aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_001588578mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_216101mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q8ZQE4macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAM98046dfra14trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

EDZ35391mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03074910mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACN45943pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

CAR61294acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACH77989acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_02659083pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

B4T6L6ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_03384190mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03376165bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ABL95938sul3sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

EDZ01315acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03386422mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAZ93366bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_04653995emrdMultidrug resistance efflux pump.

YP_209331aph3iagentamincin_b; kanamycin; lividomycin; neomycin; paromomycin; ribostamycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_04654851mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABX56805ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03161857tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002114152mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAP23220dfra17trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03352998macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_04656349pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

B4T2Y5mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ18021tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03342116bcr

YP_002113999macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_002148135bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

EDZ00970macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_002245675emrdMultidrug resistance efflux pump.

ZP_03349000pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

EDZ16383macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_02834705acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_02669680mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDY23592mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03369586mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABQ96617ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ACF68443pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

BAF63514ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ACH50811mdfa

ZP_03411063macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

B5RGC2ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

CAM91526bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03374765acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

P67388bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ACF68749ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

EDZ17875bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ABK56701dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ABO14713sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ACF66222aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

EDZ06058macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAP69665ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03163985acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABM92280dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_02834606mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF65571acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002142418mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF70214mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABU97163bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAS76288tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ACF69072tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002225954macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03383606mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAX64766mdfa

NP_863376aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

AAR05696aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ABB89119aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

EDY28870acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACH52006macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_02571053ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_03365406mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02344950bcr

ZP_02344978mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03360774macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03407784rosafosmidomycin; Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.

A9N5P5mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03215335tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ19306emrdMultidrug resistance efflux pump.

ABM92281ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

AAD26811tetgtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

YP_001598126aph3iagentamincin_b; kanamycin; lividomycin; neomycin; paromomycin; ribostamycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_03385776mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAS18380sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

CAA08845aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

AAX98731qnrafluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

CAI29521dfra15trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ACD12694bl1_acccephalosporin; e_penicillin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03364057macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAR33799bcr

EDZ14816mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03075898mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_194807aph3iagentamincin_b; kanamycin; lividomycin; neomycin; paromomycin; ribostamycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

AAX64423acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAR36740mdfa

NP_458943mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDX49058mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAD43097bl2c_pse1carbenicillin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAQ18906bl2c_pse1carbenicillin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAR35191emrdMultidrug resistance efflux pump.

EDZ22665bcr

YP_002636111acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACF62357mdfa

YP_002242988macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_002112930blebleomycin; Binding protein with a strong affinity to the bleomycin family of antibiotics, which confers resistance to these antibiotics by preventing the bleomycin-induced DNA breakage

ABA54431bl2c_pse1carbenicillin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

BAD35041dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

Q5PGK9macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAG25427bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABU97162bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAC98500sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

EDX51195ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_001976181qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ZP_03372145bcr

ACF65387mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAR59960mdfa

YP_002040106mdfa

ZP_03384170mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03376490mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001588793macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03074744bcr

ACH77571bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ACD93598qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ABX68003mdfa

NP_805793mdfa

ZP_03378969mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABG72894ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_02664562dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_02670135acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

BAF93093bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_02665238acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03413093mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAF93095aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ACN46423mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001571041macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_001746867dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03339714macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ACH85861sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03373320arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ZP_03348609acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

BAG31347bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDZ11691mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

A9MGZ7mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

B5F771ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

CAX52765dfra25trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03162450mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

B4TI56bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

BAD02328ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

EDZ18789acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAO70650tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABQ96631bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAQ51387tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

AAS76336cml_e1chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

EDZ27758mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02697285acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABD46715dfra7trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

AAL22060tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABX67745mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF88584ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_002243722mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF57106tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_02665720macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABX56819aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

EDZ33979mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

B4TSR5mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ16350mdfa

EDZ08648mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03380551mdfa

CAI38816bl1_acccephalosporin; e_penicillin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_02667966bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

AAK73751dfra14trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_02654724arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ZP_03385942mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ10287mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_04655232acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABI63550qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ZP_03076271ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

NP_806808bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ACP18864bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

Q8XFG0mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABX46818bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002894581aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_02832737pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

EDX51034mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

B4TET8mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001572785emrdMultidrug resistance efflux pump.

CAB40917sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

YP_002040143macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

BAD99521bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAO69974acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDX45196arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

EDY23885ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABA56507tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

YP_002242606acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_02697501bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03215262aac3iiadibekacin; gentamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

AAL20347mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAD09806aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_02699453acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_215072ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_002114165mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAX86813bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002226185pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_03386109mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAX64802macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03384433mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABI51985ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_002113959mdfa

NP_456779bcr

O33807bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACF68953macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

EDZ00760mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACN44670acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDX46139acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDY30695emrdMultidrug resistance efflux pump.

ACH52356emrdMultidrug resistance efflux pump.

YP_001101925aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ABO14707cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

ZP_03385738mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACF89875tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03387475macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

EDX51828bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ACF93055mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACH85850aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ACH76374macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAO68334bcr

BAD20193bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03338906mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACH85847tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

AAK61183ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03224345emrdMultidrug resistance efflux pump.

ACH51708bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

AAC32890bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03377815mdfa

ACF69388bcr

ZP_03374197mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03368312mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

NP_805529mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03376873bcr

YP_002894626bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABB77558dfra14trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03386169mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

B4TUY3mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q8Z9J7ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_03410338pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

EDZ30118bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03374661mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAL19429acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03163152acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002215971mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ05418mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03078527bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_001572361mdtnacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

Q56016ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

EDZ03237sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

AAS46623ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_04654985ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_002116141tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ37433aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

B5F954mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF61200mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q8ZQ25mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002636476mdfa

AAC83804cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

ABA54434dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

YP_002045426mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ20813acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAX65007mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02831972mdfa

ACF65056mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACN41909bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAB71033bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABB72225bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03382391macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAD04960acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

P13246aac3iiadibekacin; gentamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

ZP_02661909macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

NP_805094mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAL20826pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_03410339pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_03221871pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ACF69543bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_216088mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABA56506ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_002112963aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_002225585acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACF21687sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

EDY27177ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ACI29757bl2c_pse1carbenicillin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAF31511dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

NP_569370dfra14trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_02666474pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

CAD07712tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002148316acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03407973mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAP69663dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ABX67759mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABO41095ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ACF69174mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02685547macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_001569731bcr

ZP_03221097macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAK02055bl2c_pse1carbenicillin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03336050mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAO00292tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_03360775macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ACN41910bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACN62990bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABX66663pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_02346647acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABK56703ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03386127mdtoacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_001598135sul3sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

AAX66144bcr

ZP_03348999pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_02655872macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAD09822tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_02668435ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_002044896mdfa

ZP_02700942mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03387480mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABX56803sul3sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

BAG31352dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

CAG25425tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ABX20589bcr

YP_001587036bcr

YP_001589294acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03384645mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABQ96616dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ABX22318acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

BAF42025tetdtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_03336803mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

NP_805540mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02659039acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACH50096mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ21572mdfa

AAX63991ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_03076770mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF76693cml_e1chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

YP_002637079bcr

CAR34623bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_002142566macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03382392macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ACF68701mdfa

ZP_03368153acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

P08988aac3ivapramycin; dibekacin; gentamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

EDX43963bcr

ZP_03372962macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03223839emrdMultidrug resistance efflux pump.

ZP_02831928macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAR38902bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ACF92173bcr

YP_002040420mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q8Z6N7mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03074747macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

EDY31365mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAF63518ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

O65976bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAM91519sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

AAA75015bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_02657927mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAT36684dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

CAA08847aac3iaastromicin; gentamicin; sisomicin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

YP_002112964aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

AAN60217sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

YP_194841sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_02667258bcr

ZP_03336797emrdMultidrug resistance efflux pump.

ABO41046tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

BAD02327ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03358355tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ37602pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

YP_001598120bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03346760bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

EDZ08522ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABO41023aac3vigentamicin; sisomicin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

ZP_04654517mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAO84011aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

ACF66392acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_02830049bcr

B4TTD0mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ01437mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF69244bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_02663199tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002038873aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_02345654tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03383655mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAD02326ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ABY50545cml_e1chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

YP_001586391ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

CAD01246ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_03400607mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002041496bcr

EDX47971bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_001101921tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ABL95934cml_e1chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

AAK02051tetgtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

EDX51617tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

NP_958729tetctetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

CAA26839bl2d_oxa2cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDZ17773acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABD46710dfra14trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ABC17628qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

B5BKE4mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002039320ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_001551912tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

CAG34233dfra23trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

YP_002638807bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03076920acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAR37818mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABF47470qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ZP_03385013mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03341266pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_03075180acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABZ01840cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

CAL81500sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

AAL13153sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

EDY26241macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

BAD35037ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

AAR05750tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

AAM28884bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAR05700bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAC81324dfra19trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

YP_001591785mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABX67961macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAX86815bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAO67826ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ACH48502bcr

ABK58471bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

Q57QK4mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDY27192tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

CAJ84114bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACF91504mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABG36701cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

AAN40998aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

CAR60299acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

NP_806790tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABX46814bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002112943cml_e1chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

ZP_03353494mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAR59921macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAX65020mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAM91578aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_03401959arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ACF64586emrdMultidrug resistance efflux pump.

ABB72057dfrb6trimethoprim; Group B drug-insensitive R67 dihydrofolate reductase, which can not be inhibited by trimethoprim.

NP_458139emrdMultidrug resistance efflux pump.

CAX51337tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

AAQ18909cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

YP_002045165mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABB72866dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

CAR32042acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACN72581aph3iagentamincin_b; kanamycin; lividomycin; neomycin; paromomycin; ribostamycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_02686031mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03353770mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABS71064aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_02575120mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02344484ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAO71213emrdMultidrug resistance efflux pump.

ZP_03378953ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABX21941mdfa

ZP_03413104mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF88601aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

EDZ29814mdfa

CAL44960sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_02659147mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF76698sul3sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03368707mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02662375arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

EDY22658tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ29068mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03224589emrdMultidrug resistance efflux pump.

ABX46808bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

BAD02330bl2c_pse1carbenicillin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03386106mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_001102017ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

CAJ20142ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03385649mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAR31679ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABX22760ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

EDZ04293aac3iiadibekacin; gentamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

YP_001551943bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABX24201bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_002046276bcr

ABI17941bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03361957ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_02346813mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF88577blebleomycin; Binding protein with a strong affinity to the bleomycin family of antibiotics, which confers resistance to these antibiotics by preventing the bleomycin-induced DNA breakage

AAX64424acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002148734emrdMultidrug resistance efflux pump.

AAZ05351bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_02661867mdfa

EDX47301macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03385999mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

NP_454702ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAX67234acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ27793mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACD93602sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

CAR60300acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAT45231dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

CAD09756dfra14trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

AAS85416ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_217225bcr

ACF92773mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAR61679emrdMultidrug resistance efflux pump.

CAG34238ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ABA56504ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03412574tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAM91533aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

AAR05693aph3iagentamincin_b; kanamycin; lividomycin; neomycin; paromomycin; ribostamycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

P62594bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

BAF92949sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ABX46809bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDZ08315mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

P62580cata1chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

AAS18382aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_209370aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

CAD08290mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABX46817bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABQ96621bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002214868macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03363449ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABX69551acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAI38820dfra21trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03355318mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001551920aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ABY50547ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ACF89960acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ20916acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

B4T2Z8mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDY23251mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF67036emrdMultidrug resistance efflux pump.

AAV84026dfra5trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

YP_002042472bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

EDZ28129mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAD09800bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_02344142macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAT38900cml_e1chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

EDZ21547macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

EDY25652macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ACH85862aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_001598129dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ACH75176mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABM92277dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

AAL10704sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

BAF92953dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

EDZ18685mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001551946cata1chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

YP_002214042ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_002217166tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002637864mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAP69661ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

CAD02604bcr

NP_457596bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_02659133mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAB79606sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

AAO46870ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03374272tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABG36698dfra15trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ABX46812bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03413157acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002242951mdfa

ZP_03363022mdfa

ABB72058ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03221628mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAR38092bcr

YP_219359mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001588836mdfa

ZP_03353457mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02684807bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

EDY29574macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAD05343macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

EDZ01585mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABK28854dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ABD46712dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

Q54001tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACF88502sul3sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03384835mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAD42867ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ABO41155aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_194897tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ACF76696ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_02686017mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q57R58macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAN77728tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

P0AA00bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDZ35499ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

EDY29202mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAF93177cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

A9MQG2ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ACF88500aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_002045439aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_03360810mdfa

YP_002214869macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABI63554qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ZP_03217461mdfa

YP_001571902ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABI63549qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

EDZ05383mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_04657258macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03344183ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_03340392mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACN46687mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDX44767tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03220952mdfa

CAC81329sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

AAS76318sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

AAP92487bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDZ05294pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ACH75106tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACN48700mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABX52006ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03163398bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

NP_569415aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ABO14703sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

YP_002636110acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_02684409mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ27004macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

P74841bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDZ00438pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_03342739macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAF34178ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03354680mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF57074aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

B5FL11mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001551933mphamacrolide; Macrolide phosphotransferase

ABX46815bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03384744mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03366161bcr

NP_456105mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002044935macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAL20084mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAA08840ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

CAI29522cml_e1chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

ZP_03386406mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03368598emrdMultidrug resistance efflux pump.

BAF93114tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

CAQ51381cata1chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

ZP_03359139pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

CAA52435ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ABQ96629sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

EDY24067emrdMultidrug resistance efflux pump.

ACD93605sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

CAR61116bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

EDX49765bcr

ZP_03222019acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03385117mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03368082acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACH85869tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_03218978mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAR33462mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAR05762mphamacrolide; Macrolide phosphotransferase

ZP_03340064mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAX65350mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAR32676pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ABG80523bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDY26599mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

B4TH65mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAM98048ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

NP_455432macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAM92464aac6iiadibekacin; gentamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

CAF31516sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

EDZ23765mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

B4TJ47ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

EDY31308ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

EDY25101mdfa

CAR37023pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

EDZ25548emrdMultidrug resistance efflux pump.

EDZ01841mdfa

ABA54432bl2c_pse1carbenicillin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03217990mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002044509acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_215504acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAN52925ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_002045152mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002215709mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAT36686ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

NP_808146mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03411372mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002114946pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ABL95949cml_e1chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

BAC77165bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAR34800acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACI29347bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03365052macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_02684554acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_001590140tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03384737mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03363198macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03404009macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ACH52555mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02571342bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_002216305bcr

AAR05727aac3iiadibekacin; gentamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

ABG26447dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

EDZ31697bcr

ZP_03220884macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03077561mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACN47547acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ12172ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_209353sul3sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ACQ99520bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002045448bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03371631mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001102018aac3vigentamicin; sisomicin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

YP_001573343bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

B5BBC3mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02655829mdfa

ZP_03379816emrdMultidrug resistance efflux pump.

YP_001588124mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ02001macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAR02635aph3iagentamincin_b; kanamycin; lividomycin; neomycin; paromomycin; ribostamycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ACF88516cml_e1chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

CAJ84007sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

CAO82701dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03347831mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAR35999ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAT38902sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

B5FI34ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

CAM91481cata1chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

AAL19877macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_02832928ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAT38947ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03371009ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABX56806cml_e1chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

YP_002225919mdfa

ZP_03375947tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002114436mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAA46706tetdtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

AAN41403aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

ZP_02683734bcr

ZP_03224561aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

A9N5Q9mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF89017mdfa

EDZ02812bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

CAD04961acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAD09757ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

AAL22079bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03385110mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03075977arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ZP_03386128mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03078886bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002243220pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_03360476mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03354734mdfa

YP_001551790aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_03405689mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAI51660dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

B5FIH8mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACQ77871bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABX22897mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABF47469qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

AAS18385ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_002047183tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAD20933aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

YP_002115369arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ZP_03165798mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03386551mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ06126mdfa

CAD31708aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

EDX47746bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACH48533mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_209316cata2chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

ZP_02661910macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_002048356tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

EDY23953acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03338451mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

NP_455073acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03357083bcr

CAD20937sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03371312pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ACJ22953dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

Q8ZPP2mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02571364tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

NP_569414sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

EDZ14824mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

NP_805755macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03386666mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_02345361mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002042453tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

B4TWT6ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_02344141macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAK02049cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

EDZ06271macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_02834293mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q57JQ4bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_001598107tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

YP_001598113cata2chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

ACF62736acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACH49410acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03411064macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_209335dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03078078emrdMultidrug resistance efflux pump.

ZP_03358762mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDX46029bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

CAQ51375bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAG34240sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

BAF93180sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03368694acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03352073emrdMultidrug resistance efflux pump.

AAX86811bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAJ17558bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_02573259macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAM98047dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

EDZ25278bcr

ABA54437ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_002226908mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03362420mdfa

ZP_03216590macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABX56788bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03221593mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAO70668bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

AAR05695aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

CAC81320catb3chloramphenicol; Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.

YP_002044510acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

BAF92977cata1chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

ZP_03378846rosbfosmidomycin; Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.

ABX24021acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

BAF92950aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

CAA06312bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002332251bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABA56510sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ABO41133bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDX47443mdfa

CAM91520dfra7trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03383915acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03412557bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_002113107ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ACH51547tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABX23221mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002116162bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_001571083mdfa

AAL19878macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABK56702ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_001746874tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

CAO00285tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ABX56797dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

AAG03004sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

B5BBD5mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002638128mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABQ96619sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ABX23219mdtnacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABL95942ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

EDZ18299ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABQ02281tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_03216058pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_03345936mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

NP_455648mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABL95950ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ACF67061mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAR05733bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACF65421ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAN60214dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03377344mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAJ20146ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_02656843tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

BAF92964mphamacrolide; Macrolide phosphotransferase

AAT38945ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ACH49480macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABK28855ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

EDZ31141emrdMultidrug resistance efflux pump.

NP_803977ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAN16908ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03385303mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

BAB91583aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_03385494mdfa

ZP_02696486pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ABQ96623sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

YP_002637384pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

EDZ30075tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03367302tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABS71070tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

EDZ16202emrdMultidrug resistance efflux pump.

ACK44542bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03345100mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAR61098tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAR05697sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

YP_002142407mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03336139mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_216431mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAO89216dfra7trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

EDZ23199mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001746868ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

AAS76295cata2chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

AAL21124bcr

CAB64207cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

ACI29345bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

BAD35040ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

BAF92946aph3iagentamincin_b; kanamycin; lividomycin; neomycin; paromomycin; ribostamycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_001588794macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03161704mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAL19802mdfa

ZP_03224100emrdMultidrug resistance efflux pump.

YP_001573360tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACF91379emrdMultidrug resistance efflux pump.

ZP_03217057mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02685589mdfa

NP_455659mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002635730ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_03384961mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACH50659acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACH75435mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABA54430dfra5trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ACF90602mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_216904pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

AB0890tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAM92461catb3chloramphenicol; Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.

EDZ04366tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03413605mdfa

AAC98494cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

EDY28987arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

BAF93094aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_03373386mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002146877mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03075214acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ24555bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

CAB40922sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

AAN40996sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

AAO69378mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002142167mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAB80855bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002047203bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ABB48429sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

EDZ02781mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACJ24509qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ABB72854dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03214778bcr

ZP_03351755mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_04657675mdfa

EDX49679mdfa

ZP_03408518mdfa

ZP_03078082macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABQ96625dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ACQ99521bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002638141mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABX66203bcr

CAR59764mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_194873aac3iiadibekacin; gentamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

ACN47345tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

BAF92957sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ACF61354mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03078224mdfa

ZP_03386574mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03386188mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

B5BG16bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

BAD97357bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002214428acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03076024bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002145074ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_03352704tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ14636pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

AAS18387sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ACP18863bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03408469mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03166328ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ACH76041mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02571560acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_04657259macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_002112942ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_02700957mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDX44399acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAD09805sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

AAS76335ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ABX22319acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAS76349aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ABX46811bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

Q5PDD9ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

A9N0Y8mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q8Z7L7mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002242605acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABX46810bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03372998bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ABA56508tetctetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

AAM10643bl2_kpccarbapenem; cephalosporin; cephamycin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDX52610pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

YP_001966385bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAC20909tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_03385944mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAR36384acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDY24786acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAR40109mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABD46714ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

AAX67058bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03377501pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

CAO82704sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ACN45111macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

EDX46605pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

YP_001101926sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

YP_002146890mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAC81319ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03408602bcr

CAI64027sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

AAG24824bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAJ84014dfra19trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_04655231acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_001571460acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03412711mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACN45035mdfa

YP_001911195aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ACH75946ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAN46368dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03385835mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAQ56185aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

CAM91577aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

EDZ37458aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_02834592mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACN44669acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABX68460acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_194837aph3iagentamincin_b; kanamycin; lividomycin; neomycin; paromomycin; ribostamycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

AAN41000tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

YP_002243989mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAF92974bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACF21684dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03373588mdfa

ZP_03383336mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_001570858mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ20677bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ACH76502acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002045450sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03409672emrdMultidrug resistance efflux pump.

EDY27210dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

EDZ26615acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03356585mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03213781bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

BAD10979ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

EDZ18671mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_218117tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03363272bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ABA54435ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_002225584acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAS18375bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABF06441bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAL22260acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03378926mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02661467bcr

ACH73953acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACH85851aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_02664481acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABX20946pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

YP_002041176pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

EDZ36209bcr

AAO69642mdfa

ABX24218tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03385828mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

A9MH10mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002638988acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03386360mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAJ20144dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ABU98317dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ABX21716mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03356594mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002229045mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ17678acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACJ22955ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ACQ77823cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

EDX43966macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABU97164bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_209339sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ABX70952mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

B5QY11mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACN72590bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAD09793cata1chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

ZP_03383907tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ34403mdfa

CAF31521tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_02663601pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

YP_194844bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03351904bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ACM24779aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

ACF89101pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

YP_001101919cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

ACF70439acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ11851bcr

EDX47297emrdMultidrug resistance efflux pump.

EDY29519mdfa

CAD20939bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

Q8ZQ19mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002112967sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03404776bcr

ZP_03382712mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABA54429ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ACF63786acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABX21453mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAJ87111bl2d_oxa2cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAF68936tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_03164653acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_02575106mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02685546macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03347409emrdMultidrug resistance efflux pump.

ZP_04654863mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03387024mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF88519cata2chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

ZP_03213750mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02655873macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

EDX51618acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002044934macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAX33264bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABM92282bl2c_pse1carbenicillin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03224560aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

B5BL27ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ACH75012macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03370188mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02346204pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

AAO69975acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAR32395mdfa

CAK12750ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

EDZ29816macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAJ87116bl2d_oxa2cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAJ84117qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

YP_194909mphamacrolide; Macrolide phosphotransferase

YP_002042648acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAM91531sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

YP_209356ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ACN72587bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACH52413mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABP63664cata1chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

ACK44538aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

Q5PGY0mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

O65975bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDZ29279ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

EDZ35055tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAS46622bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

B4TES5mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

NP_806115acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDX52550mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDX45243bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABS88260dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

EDX48105bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACD93600dfra25trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

EDZ18742pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_02344754acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

Q03447aph3iagentamincin_b; kanamycin; lividomycin; neomycin; paromomycin; ribostamycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

EDZ26355mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ22787acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAF69920tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_03216380mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001588592mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABO41111sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_02346799mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001570871mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_215884macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAX52766ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_002894576cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

ZP_03364979pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_03386706mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002143711bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_02830910acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDY29251mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q8Z7L0mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03348608acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACQ77829aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ABZ01843tetgtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

YP_001552094cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

AAY87122dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

AAN16910ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

AAC98496tetgtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ABH03045bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACF65862mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF64584macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

EDX44129mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABN09669bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03343225tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03346239macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABA56512cml_e1chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

YP_002039055bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAA74573bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAC81327ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_001570088pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

AAR21617sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ABX69329bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03353166ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_002142604mdfa

BAF42020mphamacrolide; Macrolide phosphotransferase

AAS76302bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_02700387macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ACF56922bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

BAB91576tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

AAT01060bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_001551919aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_002242254ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

EDY29496macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABB72862dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

EDY28079pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

YP_002141433bcr

YP_002040142macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_002040674mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03344274acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_001911196aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ACF65233tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002894582aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_002039719acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03215830emrdMultidrug resistance efflux pump.

YP_001551918sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

NP_804485bcr

ZP_02575307pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

AAX67036tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABA56513cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

ZP_02665869mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002113506acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002215174pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_02665237acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03373116emrdMultidrug resistance efflux pump.

ABX67291mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABM92283ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_001551783aph6icstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

EDY25719pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

YP_002242987macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_02665721macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03354217ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

EDZ21621macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_02831730bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03365051macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

BAC67150tetdtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_03381672bcr

AAP92684bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_02698269ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_03080114emrdMultidrug resistance efflux pump.

NP_455431macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

EDY30331mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAA79480bl2c_pse1carbenicillin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDY22505mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACN45638bcr

ABI63551qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ABG36700sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

CAI51662ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

CAA30246bl2d_oxa2cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03338637mdfa

CAM91612tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_03383560mdtoacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAM92465bl2c_pse1carbenicillin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAW47922bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03213978acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002145820mdfa

NP_457578tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

B5QXZ9mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03340045emrdMultidrug resistance efflux pump.

P33733tetdtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_03380200pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

AAS66087dfra21trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

EDZ22551arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ABB72864bl2c_pse1carbenicillin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAS76310aph3iagentamincin_b; kanamycin; lividomycin; neomycin; paromomycin; ribostamycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

AAC98498bl2c_pse1carbenicillin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_02655417ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAX86807bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDZ07414emrdMultidrug resistance efflux pump.

EDZ30748acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

NP_806114acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_02662304mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAO82702ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03373613macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ACF88618sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03386812mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAR35831mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAD31707cml_e1chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

YP_002038872aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

EDZ05198acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03342717macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_02699452acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAC21192tetgtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

EDZ12378mdfa

A9MYM4ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAT01052bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

NP_455393mdfa

YP_215505acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_001551809tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

YP_002116340acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAN99570qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

YP_002225231ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_03356883mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACQ91137sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03214206sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03216726acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03387078emrdMultidrug resistance efflux pump.

EDZ29545pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_02667944tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002047829emrdMultidrug resistance efflux pump.

CAA63714bl2be_pere_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002228414emrdMultidrug resistance efflux pump.

EDX49534macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03219236tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_02662290mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACK44539aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_02685717mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001590162bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_002140933ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ACH50676pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_02656522acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03163266emrdMultidrug resistance efflux pump.

AAT38901cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

CAI51661ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

EDZ21805ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_03359886acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03224202emrdMultidrug resistance efflux pump.

ACN62083sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ACF66885tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

YP_002141734pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_02668919mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03378987mdfa

AAQ18908sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

YP_002894583sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03386619mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAQ51374ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03360283ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

EDZ12380macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAR36778macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_02664570tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

Q8Z824macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAA06311bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03164851macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ACF91101acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAS18381aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

AAO69389mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAF31512ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ACH50298ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

EDX46780mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002246295mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABX23643emrdMultidrug resistance efflux pump.

EDY27206sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ABL62887dfra16trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ACH77923emrdMultidrug resistance efflux pump.

ZP_03373500macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAQ56187bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACF65582bcr

CAR58198ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_03370180mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABX46807bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

B5F941mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAC81326bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDZ24164ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_03338432mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001551922dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03384704tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABA56503aph3iagentamincin_b; kanamycin; lividomycin; neomycin; paromomycin; ribostamycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ABB72857bl2c_pse1carbenicillin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

NP_807353emrdMultidrug resistance efflux pump.

ZP_03345399tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDX50196acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03381912bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

CAR33474mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001102024sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

YP_002217746emrdMultidrug resistance efflux pump.

AAZ94380dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

Q5PH16mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

NP_058295tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ACF90738arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

EDZ30759acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAX52125bl1_acccephalosporin; e_penicillin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_001598151aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_002044058ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_002045438aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

EDZ11204tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAR10958bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDZ14845acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002217361acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_001552092sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03217621macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_194840aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

BAF63517dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03385753mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

BAD07295dfra17trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

YP_001572363mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

B5RAN4mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAN16906dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

B5F6M2mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02575076acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ29959macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

EDZ07930bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_002146620mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03351184acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAD05344macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABO41168sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ABM92284bl2c_pse1carbenicillin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_001590384acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03078752bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAC81322sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ABY58043bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDZ27691acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAD05305mdfa

ZP_03162791mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABL95953sul3sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03387608mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_001571042macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_002145859macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAR34605tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03346739ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_03363477bcr

YP_002636552macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ACN44289ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_002112939sul3sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

YP_002245114bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ACQ77825tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_03407853bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_002148113tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_218315acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACI24748dfra15trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ABX56781cata2chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

ZP_04657366acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_001570595mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ27013macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

EDX45117mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03220107bcr

YP_002218389mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACN46700mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002638786tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_001551926sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_02700344mdfa

ZP_03352829bcr

YP_001746870sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03379101mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

B4T675bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03219982emrdMultidrug resistance efflux pump.

BAF42023cata2chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

EDZ26107pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_02571561acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

Q57PL1mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

B5F6A1bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ABX67960macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_001551789aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

EDY24199bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

BAD35038catb3chloramphenicol; Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.

YP_002112926bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACF91271acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ19692mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ03009acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03386401mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

B5FKZ8mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03409230mdfa

YP_002894624bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAR59752mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

NP_569411bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAG34231sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_02660552mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02833033mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF66955aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ABX56794aph3iagentamincin_b; kanamycin; lividomycin; neomycin; paromomycin; ribostamycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ABD46711ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03385608mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_001598137ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

CAA08844ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

AAS76332sul3sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ABI63553qnrsfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

YP_002227921bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

CAQ51372sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

AAT01056bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002894578tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ABK59966sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

YP_209323bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAL23335mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ35037acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_001552097sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

B5FHU0bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03356352macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03361133mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABB89122dfra5trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_02345633bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03166166emrdMultidrug resistance efflux pump.

B5R1S8ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAT36685ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03345948mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABL95935ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03354491acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDY28380bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03354409macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03409830pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_03406906rosbfosmidomycin; Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.

ZP_03165440macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAN40997aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

EDZ04861emrdMultidrug resistance efflux pump.

CAX51350tetbtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_02831751tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAC32186dfra16trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

A9MPV8bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

CAD07730bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03217864ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

AAL13155dfra10trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03366215mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ36901emrdMultidrug resistance efflux pump.

CAF31514aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_218139bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

AAL22658emrdMultidrug resistance efflux pump.

ACF61312macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_02344185mdfa

EDY27292acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABF14984ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

EDZ26789acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAF31515aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_002245096tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03357164tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAX86805bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDY25454acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002145457acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAR32043acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAA08841catb3chloramphenicol; Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.

ACF89325bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03410838bcr

CAI38809bl1_acccephalosporin; e_penicillin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDZ23167mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03343526mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02573215mdfa

ABI97038bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002043045emrdMultidrug resistance efflux pump.

AAP23222dfra17trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03221552acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABX69307tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03165769bcr

ZP_03347894mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03360465mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF67939acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAN87151ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

B4TVT9bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ABA54438ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

AAX64803macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_002639394emrdMultidrug resistance efflux pump.

ZP_03223599emrdMultidrug resistance efflux pump.

EDX50361acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03411983ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

EDZ20565tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002245290acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

B4T562mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABO41059aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ACK44537tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

YP_002043760mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDX45989mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAT38899cata1chloramphenicol; Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.

AAL19430acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03379908macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03385573mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03386103mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_02697097mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAT38946ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_02699951bcr

ZP_03077386pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ABB72859bl2c_pse1carbenicillin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAD22974bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03166329aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

AAX86809bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

NP_863375aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_194839aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_002113998macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

CAR37552mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001590869emrdMultidrug resistance efflux pump.

YP_002117438mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABB89120ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_02659708mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03343881tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAM92460aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

CAD03195emrdMultidrug resistance efflux pump.

ZP_03359058emrdMultidrug resistance efflux pump.

EDZ16437macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03409829pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

CAD03363mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ10263mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02665677mdfa

ZP_02656865bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03366947mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001572039mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAM91532aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

AAX86800bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_001101964bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDZ13441emrdMultidrug resistance efflux pump.

YP_002048539mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACI29348bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

NP_455072acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAR59037pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

AAD33243cml_e3chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

CAP69659dfra21trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

CAJ84010qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ZP_03365367tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAX68278mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

Q57QJ1mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAR39421emrdMultidrug resistance efflux pump.

EDX44433acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABL84416bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAC21193tetgtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ABA56509sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

AAV84027ereaerythromycin; Erythromycin esterase, which can inactivate erythromycin by lactone ring cleavage.

CAR32433macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_209309tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

AAL19054ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ZP_03347463mdfa

ABX21729mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAD01942mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACN72591ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03219611bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_002147194bcr

ABX65558ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

EDZ10387acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDY29851bcr

EDZ11450mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_02662649acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

NP_569416aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_002142565macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03408607tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03385896mdtpacriflavine; puromycin; t_chloride; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

A9MEJ6mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABI51984bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDZ04915ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

CAX51342bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAP72547bl1_acccephalosporin; e_penicillin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_215883macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_02683060acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABL95931dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03380399acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABB72860dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ABX46816bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABY50546bl2d_oxa10cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03163084ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

CAJ84012sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ABO41188bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACF88573tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_02573258macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_002146111pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

CAR59503mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACF57076aph33ibstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

CAD09807aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_03076810bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_02830909acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_04657635bcr

ABX21899macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

BAF92951aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_001101924aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

CAR37806mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

P67389bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

EDZ12049acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

BAF63516cml_e1chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

ZP_03217205mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_218707emrdMultidrug resistance efflux pump.

YP_002214831mdfa

CAP69660bl2d_oxa5cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAO69603macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

EDY28382tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABK34448aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

ZP_02697523tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002640141mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002115311bcr

ACQ77830sul2sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

EDZ26527mdfa

YP_002226896mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACH85856bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACF92875macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABX56775tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_03374830tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EDZ06707bcr

ZP_02831929macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ACF69484macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ACH50704acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002142927acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03404338mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_002217186bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_04657011mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_209394bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACD93604qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

AAO68943mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAP72555bl1_acccephalosporin; e_penicillin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EDZ34390macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAX86817bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_001598138cml_e1chloramphenicol; Major facilitator superfamily transporter, chloramphenicol efflux pump.

AAP82508sul3sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ABP73259bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

BAG31355sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

B5RBD4mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

YP_001649321bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002142926acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002144244emrdMultidrug resistance efflux pump.

ZP_03342386arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

YP_001101962bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_04653824tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03353669emrdMultidrug resistance efflux pump.

ABX46813bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAX65823pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

EDZ05759acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_001746863tetatetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ABG26445dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

AAM92463dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ABS71065aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ACQ77828aph6idstreptomycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

YP_001589293acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03402192mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

P0A1V8bl2d_oxa2cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAX48777dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

YP_002143693tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03403998tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

BAF93175sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_02698483mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ07555tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

B4TPI2arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ZP_03371362rosbfosmidomycin; Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.

ZP_03164918pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

Q7CP73mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EDZ34031mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

NP_805754macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03402028rosafosmidomycin; Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.

ZP_03412605mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAG34229ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

EDY26570bcr

YP_002227903tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_001551915aph3iagentamincin_b; kanamycin; lividomycin; neomycin; paromomycin; ribostamycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

BAD02331dfra17trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

EDZ34185mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAF34177dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

AAN46369ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

ZP_03406028emrdMultidrug resistance efflux pump.