ARDB-Antibiotic Resistance Genes Database

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Your Query:     Database: Resistance Gene(ALL)    Genus: Citrobacter    

202 resistance genes are found

Gene IDGene TypeResistance ProfileDescription
ZP_03835208ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

A8AI28mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EEK21277mdfa

ACA63495bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EEH94102mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAP93842bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

BAF36388bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAM11670bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAA44485bl2b_ulacephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABE11603bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EEK19422bcr

ABM89205bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAX33294bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAL85436aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

ABX72043qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

EEH94485tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACI62836qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ABC86905qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

YP_002850061macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ZP_03836256mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAD34467bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03836960qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

EEK19121tetctetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

YP_002849300mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EEK22054ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

BAD34468bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAN87698bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAN87706dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ACA63491bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAA71321bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABO09820bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABX72227qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

AAS79107bl2b_temcephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

BAF42018aph3iagentamincin_b; kanamycin; lividomycin; neomycin; paromomycin; ribostamycin; Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

ZP_03837173pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

AAR12142sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

EEK19798macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

YP_002847165mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAL59386ant2iadibekacin; gentamicin; kanamycin; sisomicin; tobramycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

NP_774964bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAA75401bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002850217arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ABV66095qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ABY82081bl3_impcarbapenem; cephalosporin; cephamycin; penicillin; Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAN87708sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

ZP_03836622mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABN51006bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABM89201bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EEK20829mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAL85435bl2d_oxa10cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

BAA12916bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

BAF95726bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_04345284emrdMultidrug resistance efflux pump.

EEH93747arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

AAL74054dfra1trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ABP88094qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

EEH92830mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03838614bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

EEK18446bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

YP_002848373acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABQ45407qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ACB41764ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

YP_002849611qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

EEH94734bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

BAF36534qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ACG63566aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

YP_002847905bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03837959tetctetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

YP_002849839pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ABX72044qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

EEH91903acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ZP_03838598tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EEK20655mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABW03157qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ABN51008bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAG34070bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

NP_775043dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

YP_002848913mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAC67147tetdtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

ZP_03835080mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

BAG14343bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABN49113bl2be_shv2e_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03835677acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

YP_002848923mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

A8AI11mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EEK19053mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

BAF91108bl3_citcarbapenem; cephalosporin; cephamycin; penicillin; Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABM89203bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABF56530bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EEH93141qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ABC60032bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002847505mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAM11668bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002848751mdfa

A8ALP9ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABF56531bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EEH92443mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EEH94502bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

EEK22390mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

AAP43508bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03837411macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABW06431dfra16trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03835678acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAM93471bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

BAA02494bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EEK22492bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAP45902qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

AAN87628bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAD55063dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ABJ56004bl1_ampccephalosporin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03837412macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABY41187qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

EEK21365acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ACJ02368sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

YP_002850060macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

AAG17724bl3_impcarbapenem; cephalosporin; cephamycin; penicillin; Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002847275ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

ABN64105bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EEK20147qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

AAR12143sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

CAO82104qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

EEH93590macbmacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABM89202bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACJ02364dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

AAR12139aac6ibamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

ABB89107ant3iaspectinomycin; streptomycin; Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.

NP_775047sul1sulfonamide; Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.

NP_775040aac3iiadibekacin; gentamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

EEK19496arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

EEH95543emrdMultidrug resistance efflux pump.

EEK19947pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

EEK18430tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABK56829bl2_kpccarbapenem; cephalosporin; cephamycin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABG56269qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

AAW78860acraacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAA54084bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACJ02370qnrafluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

AAR12140bl2d_oxa1cloxacillin; penicillin; Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

BAF42014tetdtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

EEH94885mdtmacriflavine; chloramphenicol; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

CAA35959bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAM11664bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EEK18183acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EEH91902acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

ABV66097qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

AAN87703aac3iiadibekacin; gentamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

BAC67148tetdtetracycline; Major facilitator superfamily transporter, tetracycline efflux pump.

CAA54738bl2b_ulacephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EEK20818mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ACB41763dfra12trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ACA63493bl1_moxcephalosporin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

BAB40925bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

A8APU0bacabacitracin; Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.

ZP_03837591arnapolymyxin; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

ABS30107qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

NP_775035bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

A8ACM0mdtlchloramphenicol; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ABX75315bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EEH92281mdfa

A8AH48mdtkenoxacin; norfloxacin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

EEH94995ksgakasugamycin; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.

YP_002850162bcr

CAD32304bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

BAH16555bl3_citcarbapenem; cephalosporin; cephamycin; penicillin; Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAL64954bl2be_pere_cephalosporin; monobactam; n_cephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EEH92453mdthdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

P05193bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

AAV74523bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002847014bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABN51007bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ACA63496bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

EEH94708acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EEK19799macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.

ABQ18322qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ABM89204bl2b_tem1cephalosporin_i; cephalosporin_ii; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002847888tolcacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EEH93369pbp2penicillin; The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)

ZP_03834862bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002846930emrdMultidrug resistance efflux pump.

ABD85195bl3_impcarbapenem; cephalosporin; cephamycin; penicillin; Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

P10051aac6iaamikacin; dibekacin; isepamicin; netilmicin; sisomicin; tobramycin; Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

CAP45903qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

AAK63223bl2b_ulacephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ZP_03836245mdtgdeoxycholate; fosfomycin; Major facilitator superfamily transporter. Multidrug resistance efflux pump.

ZP_03838845acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

BAF36389dfra25trimethoprim; Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.

ZP_03837521bcr

ACP31588qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

ZP_03836027mdfa

ZP_03838063mdtfdoxorubicin; erythromycin; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

EEK21364acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

AAF04388bl2be_ctxmceftazidime; cephalosporin_i; cephalosporin_ii; cephalosporin_iii; monobactam; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

CAE55180bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABX72042qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

YP_002848372acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

P22390bl2b_ulacephalosporin; penicillin; Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

YP_002848111acrbacriflavin; aminoglycoside; beta_lactam; glycylcycline; macrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

CAA27494bl1_cmy2carbapenem; cefoxitin; ceftazidime; ceftriaxone; cephalosporin; cephamycin; Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.

ABV66096qnrbfluoroquinolone; Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

EEH93692bcr

EEK22677emrdMultidrug resistance efflux pump.

EEH93591macamacrolide; Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.