ARDB-Antibiotic Resistance Genes Database

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GenusSerratia
Resistance TypeType: aac3ia
Description: Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Resistance: astromicin  gentamicin  sisomicin  
Resistance TypeType: aac3iib
Description: Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Resistance: dibekacin  gentamicin  netilmicin  sisomicin  tobramycin  
Resistance TypeType: aac6ib
Description: Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Resistance: amikacin  dibekacin  isepamicin  netilmicin  sisomicin  tobramycin  
Resistance TypeType: aac6ic
Description: Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Resistance: amikacin  dibekacin  isepamicin  netilmicin  sisomicin  tobramycin  
Resistance TypeType: acrb
Require: tolc    acra    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: acriflavin  aminoglycoside  beta_lactam  glycylcycline  macrolide  
Resistance TypeType: ant2ia
Description: Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
Resistance: dibekacin  gentamicin  kanamycin  sisomicin  tobramycin  
Resistance TypeType: ant3ia
Description: Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
Resistance: spectinomycin  streptomycin  
Resistance TypeType: aph3ia
Description: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Resistance: gentamincin_b  kanamycin  lividomycin  neomycin  paromomycin  ribostamycin  
Resistance TypeType: baca
Description: Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
Resistance: bacitracin  
Resistance TypeType: bl1_sm
Description: Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cephalosporin  
Resistance TypeType: bl2be_ctxm
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: ceftazidime  cephalosporin_i  cephalosporin_ii  cephalosporin_iii  monobactam  penicillin  
Resistance TypeType: bl2b_tem
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cephalosporin  penicillin  
Resistance TypeType: bl2b_tem1
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cephalosporin_i  cephalosporin_ii  penicillin  
Resistance TypeType: bl2d_oxa1
Description: Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cloxacillin  penicillin  
Resistance TypeType: bl2f_sme1
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: carbapenem  cephalosporin  penicillin  
Resistance TypeType: bl2_kpc
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: carbapenem  cephalosporin  cephamycin  penicillin  
Resistance TypeType: bl3_imp
Description: Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: carbapenem  cephalosporin  cephamycin  penicillin  
Resistance TypeType: bl3_vim
Description: Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: carbapenem  cephalosporin  cephamycin  penicillin  
Resistance TypeType: cata1
Description: Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
Resistance: chloramphenicol  
Resistance TypeType: catb3
Description: Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
Resistance: chloramphenicol  
Resistance TypeType: cml_e1
Description: Major facilitator superfamily transporter, chloramphenicol efflux pump.
Resistance: chloramphenicol  
Resistance TypeType: dfra1
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfra12
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfra17
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: fosa
Description: Glutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin
Resistance: fosfomycin  
Resistance TypeType: ksga
Description: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
Resistance: kasugamycin  
Resistance TypeType: mdtg
Description: Major facilitator superfamily transporter. Multidrug resistance efflux pump.
Resistance: deoxycholate  fosfomycin  
Resistance TypeType: qnrb
Description: Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.
Resistance: fluoroquinolone  
Resistance TypeType: rosa
Require: rosb    
Description: Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
Resistance: fosmidomycin  
Resistance TypeType: rosb
Require: rosa    
Description: Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
Resistance: fosmidomycin  
Resistance TypeType: tet41
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetb
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetc
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
SpeciesSerratia fonticola     Serratia marcescens     Serratia proteamaculans 568    
Database LinkNCBI Taxon ID: 613