ARDB-Antibiotic Resistance Genes Database

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GenusEscherichia
Resistance TypeType: aac3ia
Description: Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Resistance: astromicin  gentamicin  sisomicin  
Resistance TypeType: aac3iia
Description: Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Resistance: dibekacin  gentamicin  netilmicin  sisomicin  tobramycin  
Resistance TypeType: aac3iv
Description: Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Resistance: apramycin  dibekacin  gentamicin  netilmicin  sisomicin  tobramycin  
Resistance TypeType: aac3vi
Description: Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Resistance: gentamicin  sisomicin  
Resistance TypeType: aac6ia
Description: Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Resistance: amikacin  dibekacin  isepamicin  netilmicin  sisomicin  tobramycin  
Resistance TypeType: aac6ib
Description: Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Resistance: amikacin  dibekacin  isepamicin  netilmicin  sisomicin  tobramycin  
Resistance TypeType: acra
Require: acrb    tolc    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: acriflavin  aminoglycoside  beta_lactam  glycylcycline  macrolide  
Resistance TypeType: acrb
Require: tolc    acra    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: acriflavin  aminoglycoside  beta_lactam  glycylcycline  macrolide  
Resistance TypeType: ant2ia
Description: Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
Resistance: dibekacin  gentamicin  kanamycin  sisomicin  tobramycin  
Resistance TypeType: ant3ia
Description: Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
Resistance: spectinomycin  streptomycin  
Resistance TypeType: aph33ib
Description: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Resistance: streptomycin  
Resistance TypeType: aph3ia
Description: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Resistance: gentamincin_b  kanamycin  lividomycin  neomycin  paromomycin  ribostamycin  
Resistance TypeType: aph3ib
Description: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Resistance: gentamincin_b  kanamycin  lividomycin  neomycin  paromomycin  ribostamycin  
Resistance TypeType: aph3ic
Description: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Resistance: gentamincin_b  kanamycin  lividomycin  neomycin  paromomycin  ribostamycin  
Resistance TypeType: aph3iiia
Description: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Resistance: amikacin  butirosin  gentamincin_b  isepamicin  kanamycin  lividomycin  neomycin  paromomycin  ribostamycin  
Resistance TypeType: aph6ic
Description: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Resistance: streptomycin  
Resistance TypeType: aph6id
Description: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Resistance: streptomycin  
Resistance TypeType: arna
Description: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
Resistance: polymyxin  
Resistance TypeType: baca
Description: Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
Resistance: bacitracin  
Resistance TypeType: bcr
Resistance:
Resistance TypeType: bl1_acc
Description: Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cephalosporin  e_penicillin  
Resistance TypeType: bl1_ampc
Description: Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cephalosporin  
Resistance TypeType: bl1_cmy2
Description: Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: carbapenem  cefoxitin  ceftazidime  ceftriaxone  cephalosporin  cephamycin  
Resistance TypeType: bl1_ec
Description: Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cephalosporin  
Resistance TypeType: bl1_fox
Description: Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cephalosporin  
Resistance TypeType: bl1_mox
Description: Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cephalosporin  
Resistance TypeType: bl2be_ctxm
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: ceftazidime  cephalosporin_i  cephalosporin_ii  cephalosporin_iii  monobactam  penicillin  
Resistance TypeType: bl2be_per
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: e_cephalosporin  monobactam  n_cephalosporin  penicillin  
Resistance TypeType: bl2be_shv2
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: e_cephalosporin  monobactam  n_cephalosporin  penicillin  
Resistance TypeType: bl2b_tem
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cephalosporin  penicillin  
Resistance TypeType: bl2b_tem1
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cephalosporin_i  cephalosporin_ii  penicillin  
Resistance TypeType: bl2b_tem2
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cephalosporin_i  cephalosporin_ii  penicillin  
Resistance TypeType: bl2c_pse1
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: carbenicillin  penicillin  
Resistance TypeType: bl2d_oxa1
Description: Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cloxacillin  penicillin  
Resistance TypeType: bl2d_oxa10
Description: Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cloxacillin  penicillin  
Resistance TypeType: bl2d_oxa2
Description: Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cloxacillin  penicillin  
Resistance TypeType: bl2_ges
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cephalosporin  penicillin  
Resistance TypeType: bl2_kpc
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: carbapenem  cephalosporin  cephamycin  penicillin  
Resistance TypeType: bl2_veb
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cephalosporin  penicillin  
Resistance TypeType: bl3_vim
Description: Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: carbapenem  cephalosporin  cephamycin  penicillin  
Resistance TypeType: ble
Description: Binding protein with a strong affinity to the bleomycin family of antibiotics, which confers resistance to these antibiotics by preventing the bleomycin-induced DNA breakage
Resistance: bleomycin  
Resistance TypeType: cata1
Description: Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
Resistance: chloramphenicol  
Resistance TypeType: cata2
Description: Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
Resistance: chloramphenicol  
Resistance TypeType: cata3
Description: Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
Resistance: chloramphenicol  
Resistance TypeType: catb2
Description: Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
Resistance: chloramphenicol  
Resistance TypeType: catb3
Description: Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
Resistance: chloramphenicol  
Resistance TypeType: cml_e1
Description: Major facilitator superfamily transporter, chloramphenicol efflux pump.
Resistance: chloramphenicol  
Resistance TypeType: cml_e2
Description: Major facilitator superfamily transporter, chloramphenicol efflux pump.
Resistance: chloramphenicol  
Resistance TypeType: cml_e3
Description: Major facilitator superfamily transporter, chloramphenicol efflux pump.
Resistance: chloramphenicol  
Resistance TypeType: dfra1
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfra10
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfra12
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfra13
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfra14
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfra15
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfra16
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfra17
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfra22
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfra24
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfra26
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfra5
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfra7
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfrb1
Description: Group B drug-insensitive R67 dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfrb2
Description: Group B drug-insensitive R67 dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfrb3
Description: Group B drug-insensitive R67 dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: emrd
Require: emre    
Description: Multidrug resistance efflux pump.
Resistance:
Resistance TypeType: emre
Require: emrd    
Description: Multidrug resistance efflux pump.
Resistance: aminoglycoside  
Resistance TypeType: erea
Description: Erythromycin esterase, which can inactivate erythromycin by lactone ring cleavage.
Resistance: erythromycin  
Resistance TypeType: ereb
Description: Erythromycin esterase, which can inactivate erythromycin by lactone ring cleavage.
Resistance: erythromycin  
Resistance TypeType: ermb
Description: rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
Resistance: lincosamide  macrolide  streptogramin_b  
Resistance TypeType: ksga
Description: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
Resistance: kasugamycin  
Resistance TypeType: maca
Require: tolc    macb    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Resistance: macrolide  
Resistance TypeType: macb
Require: maca    tolc    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Resistance: macrolide  
Resistance TypeType: mdfa
Resistance:
Resistance TypeType: mdte
Require: mdtf    tolc    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: doxorubicin  erythromycin  
Resistance TypeType: mdtf
Require: tolc    mdte    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: doxorubicin  erythromycin  
Resistance TypeType: mdtg
Description: Major facilitator superfamily transporter. Multidrug resistance efflux pump.
Resistance: deoxycholate  fosfomycin  
Resistance TypeType: mdth
Description: Major facilitator superfamily transporter. Multidrug resistance efflux pump.
Resistance: deoxycholate  fosfomycin  
Resistance TypeType: mdtk
Description: Major facilitator superfamily transporter. Multidrug resistance efflux pump.
Resistance: enoxacin  norfloxacin  
Resistance TypeType: mdtl
Description: Major facilitator superfamily transporter. Multidrug resistance efflux pump.
Resistance: chloramphenicol  
Resistance TypeType: mdtm
Description: Major facilitator superfamily transporter. Multidrug resistance efflux pump.
Resistance: acriflavine  chloramphenicol  norfloxacin  
Resistance TypeType: mdtn
Require: mdto    mdtp    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: acriflavine  puromycin  t_chloride  
Resistance TypeType: mdto
Require: mdtn    mdtp    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: acriflavine  puromycin  t_chloride  
Resistance TypeType: mdtp
Require: mdtn    mdto    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: acriflavine  puromycin  t_chloride  
Resistance TypeType: mpha
Description: Macrolide phosphotransferase
Resistance: macrolide  
Resistance TypeType: mphb
Description: Macrolide phosphotransferase
Resistance: macrolide  
Resistance TypeType: qnra
Description: Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.
Resistance: fluoroquinolone  
Resistance TypeType: qnrb
Description: Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.
Resistance: fluoroquinolone  
Resistance TypeType: qnrs
Description: Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.
Resistance: fluoroquinolone  
Resistance TypeType: sul1
Description: Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.
Resistance: sulfonamide  
Resistance TypeType: sul2
Description: Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.
Resistance: sulfonamide  
Resistance TypeType: sul3
Description: Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.
Resistance: sulfonamide  
Resistance TypeType: tet32
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: teta
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetb
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetc
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tete
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetm
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: tolc
Require: acrb    mdtf    maca    macb    acra    mdte    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: acriflavin  aminoglycoside  beta_lactam  glycylcycline  macrolide  
SpeciesEscherichia albertii TW07627     Escherichia coli     Escherichia coli 101-1     Escherichia coli 1520     Escherichia coli 536     Escherichia coli 53638     Escherichia coli 55989     Escherichia coli 83972     Escherichia coli APEC O1     Escherichia coli B     Escherichia coli B171     Escherichia coli B7A     Escherichia coli BL21(DE3)     Escherichia coli BW2952     Escherichia coli CFT073     Escherichia coli E110019     Escherichia coli E22     Escherichia coli E24377A     Escherichia coli ED1a     Escherichia coli F11     Escherichia coli HB101     Escherichia coli HS     Escherichia coli IAI1     Escherichia coli IAI39     Escherichia coli K-12     Escherichia coli O127:H6 str. E2348/69     Escherichia coli O157:H7     Escherichia coli O157:H7 EDL933     Escherichia coli O157:H7 str. EC4024     Escherichia coli O157:H7 str. EC4042     Escherichia coli O157:H7 str. EC4045     Escherichia coli O157:H7 str. EC4076     Escherichia coli O157:H7 str. EC4113     Escherichia coli O157:H7 str. EC4115     Escherichia coli O157:H7 str. EC4196     Escherichia coli O157:H7 str. EC4206     Escherichia coli O157:H7 str. EC4401     Escherichia coli O157:H7 str. EC4486     Escherichia coli O157:H7 str. EC4501     Escherichia coli O157:H7 str. EC508     Escherichia coli O157:H7 str. EC869     Escherichia coli O157:H7 str. Sakai     Escherichia coli O157:H7 str. TW14588     Escherichia coli O6     Escherichia coli S88     Escherichia coli SE11     Escherichia coli SMS-3-5     Escherichia coli str. K-12 substr. DH10B     Escherichia coli str. K-12 substr. MG1655     Escherichia coli str. K-12 substr. W3110     Escherichia coli UMN026     Escherichia coli UTI89     Escherichia fergusonii     Escherichia fergusonii ATCC 35469     Escherichia sp. 1_1_43     Escherichia sp. 3_2_53FAA     Escherichia sp. Sam130-5B     Escherichia sp. Sflu5    
Database LinkNCBI Taxon ID: 561