ARDB-Antibiotic Resistance Genes Database

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GenusClostridium
Resistance TypeType: ant6ia
Description: Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
Resistance: streptomycin  
Resistance TypeType: baca
Description: Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
Resistance: bacitracin  
Resistance TypeType: bl2b_tem
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cephalosporin  penicillin  
Resistance TypeType: cata11
Description: Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
Resistance: chloramphenicol  
Resistance TypeType: cata15
Description: Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
Resistance: chloramphenicol  
Resistance TypeType: cata16
Description: Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
Resistance: chloramphenicol  
Resistance TypeType: ermb
Description: rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
Resistance: lincosamide  macrolide  streptogramin_b  
Resistance TypeType: ermq
Description: rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
Resistance: lincosamide  macrolide  streptogramin_b  
Resistance TypeType: mefa
Description: Major facilitator superfamily transporter, Macrolide-Lincosamide-Streptogramin B efflux pump.
Resistance: macrolide  
Resistance TypeType: tet40
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetc
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetm
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: teto
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: tetpa
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetpb
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: tetw
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: vanb
Require: vanxb    vanwb    vanrb    vanyb    vansb    vanhb    
Description: VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Resistance: vancomycin  
Resistance TypeType: vanhb
Require: vanxb    vanwb    vanb    vanrb    vanyb    vansb    
Description: VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Resistance: vancomycin  
Resistance TypeType: vanrb
Require: vanxb    vanwb    vanb    vanyb    vansb    vanhb    
Description: VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Resistance: vancomycin  
Resistance TypeType: vansb
Require: vanxb    vanwb    vanb    vanrb    vanyb    vanhb    
Description: VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Resistance: vancomycin  
Resistance TypeType: vanwb
Require: vanxb    vanb    vanrb    vanyb    vansb    vanhb    
Description: VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Resistance: vancomycin  
Resistance TypeType: vanxb
Require: vanwb    vanb    vanrb    vanyb    vansb    vanhb    
Description: VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Resistance: vancomycin  
Resistance TypeType: vanyb
Require: vanxb    vanwb    vanb    vanrb    vansb    vanhb    
Description: VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Resistance: vancomycin  
Resistance TypeType: vatb
Description: Virginiamycin A acetyltransferase, which can inactivate the target drug.
Resistance: streptogramin_a  
SpeciesClostridium acetobutylicum     Clostridium bartlettii DSM 16795     Clostridium beijerinckii NCIMB 8052     Clostridium botulinum A str. ATCC 19397     Clostridium botulinum A str. ATCC 3502     Clostridium botulinum A str. Hall     Clostridium botulinum A2 str. Kyoto     Clostridium botulinum A3 str. Loch Maree     Clostridium botulinum B str. Eklund 17B     Clostridium botulinum B1 str. Okra     Clostridium botulinum Ba4 str. 657     Clostridium botulinum Bf     Clostridium botulinum C str. Eklund     Clostridium botulinum E3 str. Alaska E43     Clostridium botulinum F str. Langeland     Clostridium botulinum NCTC 2916     Clostridium butyricum     Clostridium butyricum 5521     Clostridium butyricum E4 str. BoNT E BL5262     Clostridium difficile     Clostridium difficile 630     Clostridium difficile QCD-32g58     Clostridium hathewayi     Clostridium hiranonis DSM 13275     Clostridium kluyveri DSM 555     Clostridium kluyveri NBRC 12016     Clostridium leptum DSM 753     Clostridium methylpentosum DSM 5476     Clostridium nexile DSM 1787     Clostridium novyi NT     Clostridium perfringens     Clostridium perfringens C str. JGS1495     Clostridium perfringens CPE str. F4969     Clostridium perfringens D str. JGS1721     Clostridium perfringens E str. JGS1987     Clostridium perfringens NCTC 8239     Clostridium perfringens SM101     Clostridium perfringens str. 13     Clostridium septicum     Clostridium sp. 7_2_43FAA     Clostridium sp. CCRI-9842     Clostridium sp. M62/1     Clostridium sp. MLG055     Clostridium sp. MLG080-1     Clostridium sp. MLG101     Clostridium sp. MLG245     Clostridium sp. MLG392     Clostridium sp. MLG480     Clostridium sp. MLG661     Clostridium sp. MLG856-1    
Database LinkNCBI Taxon ID: 1485