ARDB-Antibiotic Resistance Genes Database

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GenusStaphylococcus
Resistance TypeType: aac6ib
Description: Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Resistance: amikacin  dibekacin  isepamicin  netilmicin  sisomicin  tobramycin  
Resistance TypeType: aac6ie
Description: Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Resistance: amikacin  dibekacin  isepamicin  netilmicin  sisomicin  tobramycin  
Resistance TypeType: aad9ib
Description: Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
Resistance: spectomycin  streptomycin  
Resistance TypeType: aadd
Description: Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
Resistance: kanamycin  tobramycin  
Resistance TypeType: aph3iiia
Description: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Resistance: amikacin  butirosin  gentamincin_b  isepamicin  kanamycin  lividomycin  neomycin  paromomycin  ribostamycin  
Resistance TypeType: baca
Description: Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
Resistance: bacitracin  
Resistance TypeType: bcra
Require: bcrc    
Description: ABC transporter system, bacitracin efflux pump.
Resistance: bacitracin  
Resistance TypeType: bl2a_pc
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: penicillin  
Resistance TypeType: bl2b_tem
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: cephalosporin  penicillin  
Resistance TypeType: bl2_len
Description: Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Resistance: penicillin  
Resistance TypeType: ble
Description: Binding protein with a strong affinity to the bleomycin family of antibiotics, which confers resistance to these antibiotics by preventing the bleomycin-induced DNA breakage
Resistance: bleomycin  
Resistance TypeType: cata7
Description: Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
Resistance: chloramphenicol  
Resistance TypeType: cata8
Description: Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
Resistance: chloramphenicol  
Resistance TypeType: cata9
Description: Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
Resistance: chloramphenicol  
Resistance TypeType: cml_e1
Description: Major facilitator superfamily transporter, chloramphenicol efflux pump.
Resistance: chloramphenicol  
Resistance TypeType: cml_e4
Description: Major facilitator superfamily transporter, chloramphenicol efflux pump.
Resistance: chloramphenicol  
Resistance TypeType: dfra12
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: dfra17
Description: Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
Resistance: trimethoprim  
Resistance TypeType: erma
Description: rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
Resistance: lincosamide  macrolide  streptogramin_b  
Resistance TypeType: ermb
Description: rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
Resistance: lincosamide  macrolide  streptogramin_b  
Resistance TypeType: ermc
Description: rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
Resistance: lincosamide  macrolide  streptogramin_b  
Resistance TypeType: ermy
Description: rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
Resistance: lincosamide  macrolide  streptogramin_b  
Resistance TypeType: fosb
Description: Glutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin
Resistance: fosfomycin  
Resistance TypeType: fusb
Description: Involved in the resistance (detoxification) of the fungal toxin fusaric acid.
Resistance: fusaric_acid  
Resistance TypeType: lnua
Description: Lincosamide nucleotidyltransferase.
Resistance: lincomycin  
Resistance TypeType: meca
Description: Penicillin binding protein, which has a low affinity for beta-lactams and catalyze a penicillin-insensitive transpeptidation.
Resistance: beta_lactam  
Resistance TypeType: mecr1
Description: Methicillin-resistance regulatory protein for mecA
Resistance: methicillin  
Resistance TypeType: mefa
Description: Major facilitator superfamily transporter, Macrolide-Lincosamide-Streptogramin B efflux pump.
Resistance: macrolide  
Resistance TypeType: mepa
Description: Multi antimicrobial extrusion (MATE) efflux family protein. Multidrug resistance efflux pump.
Resistance: tigecycline  
Resistance TypeType: mphc
Description: Macrolide phosphotransferase
Resistance: macrolide  
Resistance TypeType: msra
Description: ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
Resistance: lincosamide  macrolide  streptogramin_b  
Resistance TypeType: nora
Resistance:
Resistance TypeType: qac
Description: Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
Resistance: qa_compound  
Resistance TypeType: qaca
Require: qacb    
Description: Multidrug efflux pump from bacterial pathogen staphylococcus aureus. Including QacA and QacB, both of which confer resistance to various toxic organic cations but differ in that QacB mediates lower levels of resistance to divalent cations. They differed by seven nucleotide subsititutions.
Resistance: qa_compound  
Resistance TypeType: qacb
Require: qaca    
Description: Multidrug efflux pump from bacterial pathogen staphylococcus aureus. Including QacA and QacB, both of which confer resistance to various toxic organic cations but differ in that QacB mediates lower levels of resistance to divalent cations. They differed by seven nucleotide subsititutions.
Resistance: qa_compound  
Resistance TypeType: str
Description: Streptomycin resistance protein.
Resistance: streptomycin  
Resistance TypeType: tet38
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: teta
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetk
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetl
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetm
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: vana
Require: vanra    vanha    vansa    vanya    vanxa    
Description: VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Resistance: teicoplanin  vancomycin  
Resistance TypeType: vanha
Require: vanra    vansa    vana    vanya    vanxa    
Description: VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Resistance: teicoplanin  vancomycin  
Resistance TypeType: vanra
Require: vanha    vansa    vana    vanya    vanxa    
Description: VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Resistance: teicoplanin  vancomycin  
Resistance TypeType: vansa
Require: vanra    vanha    vana    vanya    vanxa    
Description: VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Resistance: teicoplanin  vancomycin  
Resistance TypeType: vanxa
Require: vanra    vanha    vansa    vana    vanya    
Description: VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Resistance: teicoplanin  vancomycin  
Resistance TypeType: vanya
Require: vanra    vanha    vansa    vana    vanxa    
Description: VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Resistance: teicoplanin  vancomycin  
Resistance TypeType: vanz
Description: VanZ confers low-level VanZ confers low-level resistance to the glycopeptide antibiotic teicoplanin.
Resistance: teicoplanin  
Resistance TypeType: vata
Description: Virginiamycin A acetyltransferase, which can inactivate the target drug.
Resistance: streptogramin_a  
Resistance TypeType: vatb
Description: Virginiamycin A acetyltransferase, which can inactivate the target drug.
Resistance: streptogramin_a  
Resistance TypeType: vatc
Description: Virginiamycin A acetyltransferase, which can inactivate the target drug.
Resistance: streptogramin_a  
Resistance TypeType: vgaa
Description: ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
Resistance: streptogramin_a  
Resistance TypeType: vgab
Description: ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
Resistance: streptogramin_a  
Resistance TypeType: vgba
Description: Streptogramin B Lyase, which can deactivate the target drug by hydrolysis.
Resistance: streptogramin_b  
Resistance TypeType: vgbb
Description: Streptogramin B Lyase, which can deactivate the target drug by hydrolysis.
Resistance: streptogramin_b  
SpeciesStaphylococcus aureus     Staphylococcus aureus RF122     Staphylococcus aureus RN4220     Staphylococcus aureus subsp. aureus COL     Staphylococcus aureus subsp. aureus JH1     Staphylococcus aureus subsp. aureus JH9     Staphylococcus aureus subsp. aureus MN8     Staphylococcus aureus subsp. aureus MRSA252     Staphylococcus aureus subsp. aureus MSSA476     Staphylococcus aureus subsp. aureus Mu3     Staphylococcus aureus subsp. aureus Mu50     Staphylococcus aureus subsp. aureus MW2     Staphylococcus aureus subsp. aureus N315     Staphylococcus aureus subsp. aureus NCTC 8325     Staphylococcus aureus subsp. aureus str. JKD6008     Staphylococcus aureus subsp. aureus str. JKD6009     Staphylococcus aureus subsp. aureus str. Newman     Staphylococcus aureus subsp. aureus TCH60     Staphylococcus aureus subsp. aureus USA300     Staphylococcus aureus subsp. aureus USA300_FPR3757     Staphylococcus aureus subsp. aureus USA300_TCH1516     Staphylococcus aureus subsp. aureus USA300_TCH959     Staphylococcus capitis     Staphylococcus capitis SK14     Staphylococcus carnosus subsp. carnosus TM300     Staphylococcus chromogenes     Staphylococcus cohnii     Staphylococcus epidermidis     Staphylococcus epidermidis RP62A     Staphylococcus equorum     Staphylococcus equorum subsp. equorum     Staphylococcus haemolyticus     Staphylococcus haemolyticus JCSC1435     Staphylococcus hominis     Staphylococcus hominis SK119     Staphylococcus hyicus     Staphylococcus intermedius     Staphylococcus kloosii     Staphylococcus lentus     Staphylococcus pseudintermedius     Staphylococcus saprophyticus     Staphylococcus saprophyticus subsp. saprophyticus     Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305     Staphylococcus sciuri     Staphylococcus simulans     Staphylococcus sp.     Staphylococcus sp. 693-2     Staphylococcus sp. ST94     Staphylococcus vitulinus     Staphylococcus warneri     Staphylococcus warneri L37603     Staphylococcus xylosus    
Database LinkNCBI Taxon ID: 1279