ARDB-Antibiotic Resistance Genes Database

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Antibioticdoxorubicin
DescriptionAntineoplastic antibiotic obtained from Streptomyces peucetius. It is a hydroxy derivative of DAUNORUBICIN and is used in treatment of both leukemia and solid tumors.
Action Targettopoisomerase II inhibitor
SynonymsAdriblastina   ADR
Resistance TypeType: blt
Description: Major facilitator superfamily transporter. Multidrug resistance efflux pump.
Resistance: chloramphenicol  doxorubicin  fluoroquinolone  puromycin  
Resistance TypeType: mdte
Require: mdtf    tolc    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: doxorubicin  erythromycin  
Resistance TypeType: mdtf
Require: tolc    mdte    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: doxorubicin  erythromycin  
Database LinksKEGG DRUG: D03899
ChEBI ID: CHEBI: 28748