ARDB-Antibiotic Resistance Genes Database

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Antibiotictetracycline
DescriptionAn antibiotic originally produced by Streptomyces viridifaciens, but used mostly in synthetic form. It is an inhibitor of aminoacyl-tRNA binding during protein synthesis.
Action Target30S ribosomal subunit, protein synthesis inhibitor
SynonymsTC   Sumycin
Resistance TypeType: mexa
Require: mexb    oprm    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: aminoglycoside  beta_lactam  fluoroquinolone  tetracycline  tigecycline  
Resistance TypeType: mexb
Require: oprm    mexa    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: aminoglycoside  beta_lactam  fluoroquinolone  tetracycline  tigecycline  
Resistance TypeType: oprm
Require: mexy    mexb    mexw    mexa    mexv    mexk    mexj    mexx    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: aminoglycoside  beta_lactam  fluoroquinolone  tetracycline  tigecycline  
Resistance TypeType: otra
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: otrb
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tcr3
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tet
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: tet30
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tet31
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tet32
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: tet33
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tet34
Description: Xanthine-guanine phosphoribosyltransferase. Mechanism detail unknown.
Resistance: tetracycline  
Resistance TypeType: tet36
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: tet37
Description: Flavoproteins. Mechanism detail unknown. Only one such protein found in oral metagenome.
Resistance: tetracycline  
Resistance TypeType: tet38
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tet39
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tet40
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tet41
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: teta
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetb
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetc
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetd
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tete
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetg
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: teth
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetj
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetk
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetl
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetm
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: teto
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: tetpa
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetpb
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: tetq
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: tets
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: tett
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: tetu
Description: Tetracycline resistance other mechanisms.
Resistance: tetracycline  
Resistance TypeType: tetv
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetw
Description: Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Resistance: tetracycline  
Resistance TypeType: tetx
Description: NADP-requiring oxidoreductase, an enzyme that can modify tetracycline. Mechanism detail unknown.
Resistance: tetracycline  
Resistance TypeType: tety
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Resistance TypeType: tetz
Description: Major facilitator superfamily transporter, tetracycline efflux pump.
Resistance: tetracycline  
Database LinksKEGG DRUG: D00201
ChEBI ID: CHEBI: 26895