ARDB-Antibiotic Resistance Genes Database

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Antibioticroxithromycin
DescriptionSemisynthetic derivative of erythromycin. It is concentrated by human phagocytes and is bioactive intracellularly. While the drug is active against a wide spectrum of pathogens, it is particularly effective in the treatment of respiratory and genital tract infections.
Action Target23S rRNA of 50S ribosomal subunit, protein synthesis inhibitor
SynonymsRulide   RXM
Resistance TypeType: mexc
Require: oprj    mexd    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: erythromycin  fluoroquinolone  glycylcycline  roxithromycin  
Resistance TypeType: mexd
Require: oprj    mexc    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: erythromycin  fluoroquinolone  glycylcycline  roxithromycin  
Resistance TypeType: oprj
Require: mexd    mexc    
Description: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Resistance: erythromycin  fluoroquinolone  glycylcycline  roxithromycin  
Database LinksKEGG DRUG: D01710
ChEBI ID: CHEBI: 48844