ARDB-Antibiotic Resistance Genes Database

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Antibiotickanamycin
DescriptionAntibiotic complex produced by Streptomyces kanamyceticus from Japanese soil. Comprises 3 components: kanamycin A, the major component, and kanamycins B and C, the minor components.
Action Target16S rRNA of 30S ribosomal subunit, protein synthesis inhibitor
SynonymsKM   Kanamycin sulfate
Resistance TypeType: aac3iii
Description: Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Resistance: dibekacin  gentamicin  kanamycin  lividomycin  neomycin  paromomycin  sisomicin  tobramycin  
Resistance TypeType: aadd
Description: Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
Resistance: kanamycin  tobramycin  
Resistance TypeType: ant2ia
Description: Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
Resistance: dibekacin  gentamicin  kanamycin  sisomicin  tobramycin  
Resistance TypeType: ant2ib
Description: Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
Resistance: dibekacin  gentamicin  kanamycin  sisomicin  tobramycin  
Resistance TypeType: aph3ia
Description: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Resistance: gentamincin_b  kanamycin  lividomycin  neomycin  paromomycin  ribostamycin  
Resistance TypeType: aph3ib
Description: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Resistance: gentamincin_b  kanamycin  lividomycin  neomycin  paromomycin  ribostamycin  
Resistance TypeType: aph3ic
Description: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Resistance: gentamincin_b  kanamycin  lividomycin  neomycin  paromomycin  ribostamycin  
Resistance TypeType: aph3iia
Resistance: butirosin  gentamincin_b  kanamycin  neomycin  paromomycin  ribostamycin  
Resistance TypeType: aph3iiia
Description: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Resistance: amikacin  butirosin  gentamincin_b  isepamicin  kanamycin  lividomycin  neomycin  paromomycin  ribostamycin  
Resistance TypeType: aph3iva
Description: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Resistance: butirosin  kanamycin  neomycin  paromomycin  ribostamycin  
Resistance TypeType: aph3via
Description: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Resistance: amikacin  butirosin  gentamicin_b  isepamicin  kanamycin  neomycin  paromomycin  ribostamycin  
Resistance TypeType: aph3viia
Description: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Resistance: kanamycin  neomycin  
Resistance TypeType: norm
Description: Multi antimicrobial extrusion (MATE) efflux family protein. Multidrug resistance efflux pump.
Resistance: ciprofloxacin  kanamycin  norfloxacin  streptomycin  tigecycline  
Database LinksKEGG DRUG: D03262
ChEBI ID: CHEBI: 24951