ARDB-Antibiotic Resistance Genes Database

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Antibioticimipenem
DescriptionSemisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.
Action Targetpenicillin binding protein 2 (PBP2), cell wall synthesis inhibitor
SynonymsIPM   Imipenem anhydrous
Database LinksKEGG DRUG: D04515
ChEBI ID: CHEBI: 46765