ARDB-Antibiotic Resistance Genes Database

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AccessionNP_815955
Sequence StatusNON-REDUNDANT
COMPLETE
Resistance Typevansb
Requirevanxb    vanwb    vanb    vanrb    vanyb    vanhb    
DescriptionVanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Antibiotic Resistancevancomycin
OrganismEnterococcus faecalis V583
Gene Ontology (GO)Molecular Function
D-alanine-D-alanine ligase activity [GO:0008716]


Biological Process
drug target replacement [AR:0001002]
vancomycin resistance [AR:0000028]
COGCOG642
Description: Signal transduction histidine kinase
Function: Signal transduction mechanisms;

COG3850
Description: Signal transduction histidine kinase, nitrate/nitrite-specific
Function: Signal transduction mechanisms;

CDD141075
119399
28956: HATPase_c
33640: NarQ
Database LinkNCBI Protein: NP_815955
NCBI DNA: NC_004668      
Protein Sequence